Structure of PDB 5t5h Chain X Binding Site BS02

Receptor Information
>5t5h Chain X (length=109) Species: 5693 (Trypanosoma cruzi) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AYTRPQFRRPHTYRRPSMSAISNKWDAFRVIRYPLTTDKAMKKIEENNTL
TFIVDSNANKTEIKKAMRKLYQVKAVKVNTLIRPDGLKKAYIRLSASYDA
LETANKMGL
Ligand information
>5t5h Chain B (length=941) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acugcagaccguacucaucaccgcaucagguccccaagcauacaaugcuc
ugguacauagagaaagguacacucagggaagucggcaaaauagaugcgua
aguucgcaagaagcauuggcucugagggcaacaacucagaacugcuuacg
gcggggaauccaacuguauaauuaaaacauagguuugugaugcauccaag
ugguguaugucgcaaacugauuucugcccagugcucugugaagagguuca
ccggcgcggguaaacggcaagguagccaaaugccucgucuuccaauuaga
gacgcgcaugaauggauuaaugagauucccucugucccgaguuacuaucu
agcgaaacgacagucaagggaacggacuugaagggcuaagcggggaaaga
agacccuguugaguuugacuccagucuggcucugugaggcgagcuucacu
uaucgaaugaagagaccaauggguuucgcguagucugcgggcuaugcacc
gucucugaaccaacggagucuuguuucgagacaucugccagauggggagu
uuggcuggggcggcauaucuguuacacgacaacgcagguguccuaaggcg
agcucagugggaucucacguagaacacaagcguaaaagcuugcuugauua
acgauuuccaguacgaaucgagacugcgaaagcaaggccagcgauccuuu
gcguaugaacaaaucauaccagaggugucagaauaauuaccacagggaua
acuggcuuauccuucgaugucggcucuuccuaaccuagcggcuaaggguu
ggauuguucacccacugacagggaacgugagcuggguuuagaccgucgug
agacagguugguuuuacccuacuuagcuggaaauugcgagaaaaaaaaaa
uuuuuuaaaauuuuuuuuuuuuuuacuugguacgaaaaaaa
....................<<......>>......<<<<.....>>>>.
.......<<<<....<<<<.<<<<.<<...............<<<<<...
............>>>>><<.<<<<<<........>>>>>>.>>.......
...<<<<<<<<<..<<<.........>>>..<<<<<<<....<<<<....
.>>>>......>>>>>>>...<<...<<..<<<<<<.<<<<<....>>>>
>......>>>>..>>>>.......<...........<<<<<.......>>
>>>.....>.....>>....>>.>>>>>>>.....>>.>>>>>>>>.>>>
>............<<<<<........>>>>>..<<<<<<<..<<<.<<..
....<<<<.<.<<<<..<<<<<.<<<<<<<...<<<<<<<..>>>>>>>.
..<<<<<.....<<<<....<<.....<<<<<<<......>>>>>>>.>>
.................>>>>...>>>>>.......>>>>>>>..>>>>>
...<<<.....>>>..<<<<<<...........>>>>>>..<<...<<<<
<<<...<<<<<..>>>>>.....<<......>>....>>>>>>>...<<.
..<<<<<.......>>>>>..>>.<<<....>>>.>>........<<<<<
<.<<<<<.......>>>>>>>>>>>.........>>>>...>>>>>....
...<<....>.>.......<<<<<.<<<<<<..<<<<<<.>>>>..>>.<
<<.........>>>.....>>>>>..>...>>>.>>....<<<<<<<...
.>>>.>>>>....>>..>>>.>>>>>>>..................<<<.
.>>>..<<...>>.<<<<<<...<.......>...>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5t5h Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit.
Resolution2.54 Å
Binding residue
(original residue number in PDB)		P82 Q83 N143 K144 T145 K148 I166 K172
Binding residue
(residue number reindexed from 1)		P5 Q6 N59 K60 T61 K64 I82 K88
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5t5h, PDBe:5t5h, PDBj:5t5h
PDBsum5t5h
PubMed27791004
UniProtQ4E2Y1

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