Structure of PDB 2zvp Chain X Binding Site BS02

Receptor Information
>2zvp Chain X (length=289) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LDVFRRELVDVEGIPLFWSIAEHWSQVESFEARPDDILISTYPKSGTTWV
SEILDLIYNNGDAEKCKRDAIYKRVPFMELIIPGITNGVEMLNNMPSPRI
VKTHLPVQLLPSSFWKNDCKIIYVARNAKDVVVSYYYFYQMAKIHPEPGT
WEEFLEKFMAGQVSFGPWYDHVKSWWEKRKEYRILYLFYEDMKENPKCEI
QKILKFLEKDIPEEILNKILYHSSFSVMKENPSANYTTMMKEEMDHSVSP
FMRKGISGDWKNQFTVAQYEKFEEDYVKKMEDSTLKFRS
Ligand information
Ligand IDNPO
InChIInChI=1S/C6H5NO3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H
InChIKeyBTJIUGUIPKRLHP-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341Oc1ccc(cc1)[N+]([O-])=O
ACDLabs 10.04O=[N+]([O-])c1ccc(O)cc1
OpenEye OEToolkits 1.5.0c1cc(ccc1[N+](=O)[O-])O
FormulaC6 H5 N O3
NameP-NITROPHENOL
ChEMBLCHEMBL14130
DrugBankDB04417
ZINCZINC000034828682
PDB chain2zvp Chain X Residue 1201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2zvp Structural basis for the broad range substrate specificity of a novel mouse cytosolic sulfotransferase--mSULT1D1
Resolution1.3 Å
Binding residue
(original residue number in PDB)		F21 F81 K106 H108 F142 H149 M248
Binding residue
(residue number reindexed from 1)		F17 F77 K102 H104 F138 H145 M244
Annotation score1
Enzymatic activity
Enzyme Commision number 2.8.2.-
Gene Ontology
Molecular Function
GO:0004062 aryl sulfotransferase activity
GO:0008146 sulfotransferase activity
GO:0016740 transferase activity
Biological Process
GO:0000103 sulfate assimilation
GO:0006584 catecholamine metabolic process
GO:0006629 lipid metabolic process
GO:0051923 sulfation
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2zvp, PDBe:2zvp, PDBj:2zvp
PDBsum2zvp
PubMed19073143
UniProtQ3UZZ6|ST1D1_MOUSE Sulfotransferase 1 family member D1 (Gene Name=Sult1d1)

[Back to BioLiP]