Structure of PDB 2o5l Chain X Binding Site BS02

Receptor Information

>2o5l Chain X (length=152) Species: 9796 (Equus caballus)

GLSDGEWQQVLNVWGKVEADIAGHGQEVLIRLFTGHPETLEKFDKFKHLK
TEAEMKASEDLKKHGTVVLTALGGILKKKGHHEAELKPLAQSHATKHKIP
IKYLEFISDAIIHVLHSKHPGDFGADAQGAMTKALELFRNDIAAKYKELG
FQ

Ligand information

• Ligand ID: MOH
• InChI: InChI=1S/CH4O/c1-2/h2H,1H3
• InChIKey: OKKJLVBELUTLKV-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.352
  OpenEye OEToolkits 1.7.0: CO
  ACDLabs 11.02: OC
• Formula: C H4 O
• Name: METHANOL
• ChEMBL: CHEMBL14688
• PDB chain: 2o5l Chain X Residue 160

Receptor-Ligand Complex Structure

Structure summary

• PDB: 2o5l Crystal structures of manganese- and cobalt-substituted myoglobin in complex with NO and nitrite reveal unusual ligand conformations.
• Resolution: 1.7 Å
• Binding residue (original residue number in PDB): H64 V68
• Binding residue (residue number reindexed from 1): H64 V68
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 1.11.1.-
  1.7.-.-

Gene Ontology

Molecular Function

• GO:0004601 peroxidase activity
• GO:0005344 oxygen carrier activity
• GO:0016491 oxidoreductase activity
• GO:0019825 oxygen binding
• GO:0020037 heme binding
• GO:0046872 metal ion binding
• GO:0098809 nitrite reductase activity

Biological Process

• GO:0015671 oxygen transport
• GO:0019430 removal of superoxide radicals

Cellular Component

• GO:0005737 cytoplasm
• GO:0016528 sarcoplasm

External links

• PDB: RCSB:2o5l, PDBe:2o5l, PDBj:2o5l
• PDBsum: 2o5l
• PubMed: 17905436
• UniProt: P68082|MYG_HORSE Myoglobin (Gene Name=MB)