Structure of PDB 2gtf Chain X Binding Site BS02

Receptor Information
>2gtf Chain X (length=180) Species: 13249 (Rhodnius prolixus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDCSTNISPKQGLDKAKYFSGKWYVTHFLDKDPQVTDQYCSSFTPRESDG
TVKEALYHYNANKKTSFYNIGEGKLESSGLQYTAKYKTVDKKKAVLKEAD
EKNSYTLTVLEADDSSALVHICLREGSKDLGDLYTVLTHQKDAEPSAKVK
SAVTQAGLQLSQFVGTKDLGCQYDDQFTSL
Ligand information
Ligand IDP1R
InChIInChI=1S/C4H4N2/c1-2-5-4-6-3-1/h1-4H
InChIKeyCZPWVGJYEJSRLH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		c1cncnc1
ACDLabs 10.04n1cccnc1
FormulaC4 H4 N2
NamePYRIMIDINE
ChEMBLCHEMBL15562
DrugBank
ZINCZINC000000895216
PDB chain2gtf Chain X Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2gtf The crystal structure of nitrophorin 2. A trifunctional antihemostatic protein from the saliva of Rhodnius prolixus
Resolution1.4 Å
Binding residue
(original residue number in PDB)		I120 L122 L132
Binding residue
(residue number reindexed from 1)		I121 L123 L133
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0051381 histamine binding
GO:0070026 nitric oxide binding
Biological Process
GO:0042311 vasodilation
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2gtf, PDBe:2gtf, PDBj:2gtf
PDBsum2gtf
PubMed
UniProtQ26241|NP2_RHOPR Nitrophorin-2

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