Structure of PDB 8ovj Chain W Binding Site BS02

Receptor Information
>8ovj Chain W (length=118) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KCGSRRKARRAHFQAPSHVRRVLMSAPLSKELRAKYNVRAMPVRKDDEVI
VKRGTFKGREGKVTACYRLKWVILIDKVNREKANGSTVAVGIHPSNVEIT
KLKLTHHRKSILERKDRS
Ligand information
>8ovj Chain 7 (length=164) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aacgugucgcgauggaugacuuggcuuccuauuucguugaagaacgcagu
aaagugcgauaagugguaucaauugcagaacauucaauuaccgaaucuuu
gaacgcaaacggcgcaugggagaagcucgugucauccccgugcaugccau
auucucagugucga
.........................................<<<<<<.((
.....>>>.....<<<<<......))............>>>>.>...>>>
....<<.....>><<<<<<<....<<....>>....>>>>>>>.......
..............
Receptor-Ligand Complex Structure
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PDB8ovj Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		R10 R13 R14 F17 Q18 S21 H22 R25 K49 Y71 R72 H110 R118
Binding residue
(residue number reindexed from 1)		R6 R9 R10 F13 Q14 S17 H18 R21 K45 Y67 R68 H106 R114
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:0031981 nuclear lumen
GO:0097014 ciliary plasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ovj, PDBe:8ovj, PDBj:8ovj
PDBsum8ovj
PubMed38722744
UniProtQ4QAC5

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