Structure of PDB 7xti Chain W Binding Site BS02

Receptor Information
>7xti Chain W (length=533) Species: 460519 (Komagataella phaffii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQRLLIPTVDDPGIWGVKVRLGKEKDVVRQILKKKLAREGTKNPLEIYSA
FQRDSFKGHVYIEARKAEAINDALKGNVNVFSNNSKFLVGIVEYKDLLRP
VKSSDVKLTRGSYVRVKNGKFKGDLAQVDEVLENGLEARLKLVPRLDYGF
RPAQRLFSEAEARVHEPTIRRDRDGFVTYGGEEYYEGFLYKTFRLQNLIV
NSINPTLNELSLFQSNEESTTIDLSTIADSLKETAKNLVSFQPGDNVEII
NGELNHLTGTVSSVNQSTIVSVRLHSDDDTINSETVEIPTSDLRKIFNVG
DHVRVIHGKHTDDTGLIVEVNGDKVEFISNQTKRTVIVFSNYLIKSTDST
VSINESGRFELHDLVQVNSDLVGIVIRAQKDSFDVLCSDGKLLSLPPVSI
YSKLNLNPNQQIAIDSNGVEVKVGDTVREFTGERRQGTILHVYRNFLFLR
SREIVENQGVFVTSSNRVKTIRDPTLNKTVKIRQGGYKGKIGIVKEANGD
RFRVELHNPNKTIPIPCSFLLIESTHGWVPYED
Ligand information
>7xti Chain T (length=85) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gtacgcgctgtcccccgcgttttaaccgccaaggggattacacccaagac
accaggcacgagacagaaaaaaacaacgaaaacgg
Receptor-Ligand Complex Structure
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PDB7xti Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		R431 Q433
Binding residue
(residue number reindexed from 1)		R194 Q196
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003711 transcription elongation factor activity
GO:0003729 mRNA binding
GO:0140463 chromatin-protein adaptor activity
Biological Process
GO:0006325 chromatin organization
GO:0006354 DNA-templated transcription elongation
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006368 transcription elongation by RNA polymerase II
GO:0032784 regulation of DNA-templated transcription elongation
Cellular Component
GO:0005634 nucleus
GO:0032044 DSIF complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xti, PDBe:7xti, PDBj:7xti
PDBsum7xti
PubMed35981082
UniProtC4R370

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