Structure of PDB 7wbw Chain W Binding Site BS02

Receptor Information
>7wbw Chain W (length=275) Species: 460519 (Komagataella phaffii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQRLLIPTVDDPGIWGVKVRLGKEKDVVRQILKKKLAREGTKNPLEIYSA
FQRDSFKGHVYIEARKAEAINDALKGNVNVFSNNSKFLVGIVEYKDLLRP
VKLTRGSYVRVKNGKFKGDLAQVDEVLENGLEARLKLVPRLDYGKDLSYT
SKFRPAQRLFSEAEARVHEIRRDRDGFVTYGGEEYYEGFLYKTFRLQNLI
VNSINPTLNELSLFDPTLNKTVKIRQGGYKGKIGIVKEANGDRFRVELHN
PNKTIPIPCSFLLIESTHGWVPYED
Ligand information
>7wbw Chain T (length=154) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcagaatcccggtgccgaggccgctcaattggtcgtagacagctctagc
accgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaaggg
gattacacccaagacaccaggcacgagacagcaaaaaacaacgaaaacgg
ccac
Receptor-Ligand Complex Structure
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PDB7wbw Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome.
Resolution7.1 Å
Binding residue
(original residue number in PDB)		N330 K332 R431
Binding residue
(residue number reindexed from 1)		N113 K115 R195
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003711 transcription elongation factor activity
GO:0003729 mRNA binding
GO:0140463 chromatin-protein adaptor activity
Biological Process
GO:0006325 chromatin organization
GO:0006354 DNA-templated transcription elongation
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006368 transcription elongation by RNA polymerase II
GO:0032784 regulation of DNA-templated transcription elongation
Cellular Component
GO:0005634 nucleus
GO:0032044 DSIF complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7wbw, PDBe:7wbw, PDBj:7wbw
PDBsum7wbw
PubMed37120012
UniProtC4R370

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