Structure of PDB 6j50 Chain W Binding Site BS02

Receptor Information
>6j50 Chain W (length=275) Species: 644223 (Komagataella phaffii GS115) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQRLLIPTVDDPGIWGVKVRLGKEKDVVRQILKKKLAREGTKNPLEIYSA
FQRDSFKGHVYIEARKAEAINDALKGNVNVFSNNSKFLVGIVEYKDLLRP
VKLTRGSYVRVKNGKFKGDLAQVDEVLENGLEARLKLVPRLDYGKDLSYT
SKFRPAQRLFSEAEARVHEIRRDRDGFVTYGGEEYYEGFLYKTFRLQNLI
VNSINPTLNELSLFDPTLNKTVKIRQGGYKGKIGIVKEANGDRFRVELHN
PNKTIPIPCSFLLIESTHGWVPYED
Ligand information
>6j50 Chain N (length=123) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tctcgtgcctggtgtctttaatccccttggcggttaaaacgcgggggaca
gcgcgtacgtgcgtttaagcggtgctagagctgtctacgaccaattgagc
ggcctcggcaccgggattctgat
Receptor-Ligand Complex Structure
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PDB6j50 Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Resolution4.7 Å
Binding residue
(original residue number in PDB)		K334 K386
Binding residue
(residue number reindexed from 1)		K117 K152
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003711 transcription elongation factor activity
GO:0003729 mRNA binding
GO:0140463 chromatin-protein adaptor activity
Biological Process
GO:0006325 chromatin organization
GO:0006354 DNA-templated transcription elongation
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006368 transcription elongation by RNA polymerase II
GO:0032784 regulation of DNA-templated transcription elongation
Cellular Component
GO:0005634 nucleus
GO:0032044 DSIF complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6j50, PDBe:6j50, PDBj:6j50
PDBsum6j50
PubMed30733384
UniProtC4R370

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