Structure of PDB 6gym Chain W Binding Site BS02

Receptor Information
>6gym Chain W (length=258) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PIDDIVKNLLKFVVRGFYGGSFVLVLDAILFHSVLAEDDLKQLLSINKTE
LGPLIARLRSDRLISIHKQREYPPNSKSVERVYYYVKYPHAIDAIKWKVH
QVVQRLKDDLDKNSEPNGYMCPICLTKYTQLEAVQLLNFDRTEFLCSLCD
EPLVEDDSGKKNKEKQDKLNRLMDQIQPIIDSLKKIDDSRIAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
EDEFEDVT
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6gym Chain W Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6gym Promoter Distortion and Opening in the RNA Polymerase II Cleft.
Resolution6.7 Å
Binding residue
(original residue number in PDB)		I126 C127 C152
Binding residue
(residue number reindexed from 1)		I123 C124 C149
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006367 transcription initiation at RNA polymerase II promoter

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Biological Process
External links
PDB RCSB:6gym, PDBe:6gym, PDBj:6gym
PDBsum6gym
PubMed30472190
UniProtP36100|T2EA_YEAST Transcription initiation factor IIE subunit alpha (Gene Name=TFA1)

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