Structure of PDB 5hl7 Chain W Binding Site BS02
Receptor Information
>5hl7 Chain W (length=57) Species:
93061
(Staphylococcus aureus subsp. aureus NCTC 8325) [
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AKLQITLTRSVIGRPETQRKTVEALGLKKTNSSVVVEDNPAIRGQINKVK
HLVTVEE
Ligand information
>5hl7 Chain Y (length=114) [
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ucuggugacuauagcaaggaggucacaccuguucccaugccgaacacaga
aguuaaggucuuuagcgacgaugguagccaacuuacguuccgcuagagua
gaacguugccaggc
.<<.<..<.....<<<<<<<......<<<<<...............>>>.
.>>.....>>>>>.>><....<....<.<............>.>.....>
...>..>..>.>>.
Receptor-Ligand Complex Structure
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PDB
5hl7
A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism.
Resolution
3.55 Å
Binding residue
(original residue number in PDB)
Q19 H52
Binding residue
(residue number reindexed from 1)
Q18 H51
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003735
structural constituent of ribosome
Biological Process
GO:0006412
translation
Cellular Component
GO:0005840
ribosome
GO:0015934
large ribosomal subunit
GO:0022625
cytosolic large ribosomal subunit
GO:1990904
ribonucleoprotein complex
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External links
PDB
RCSB:5hl7
,
PDBe:5hl7
,
PDBj:5hl7
PDBsum
5hl7
PubMed
27958389
UniProt
P0A0G2
|RL30_STAA8 Large ribosomal subunit protein uL30 (Gene Name=rpmD)
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