Structure of PDB 8y6o Chain V Binding Site BS02

Receptor Information
>8y6o Chain V (length=101) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGKRYFCDYCDRSFQDNLHNRKKHLNGLQHLKAKKVWYDMFRDAAAILLD
EQNKRPCRKFLLTGQCDFGSNCRFSHMSERDLQELSIQVEEERRAREWLL
D
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8y6o Chain V Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8y6o Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome
Resolution3.38 Å
Binding residue
(original residue number in PDB)		C7 C10 H24 H30
Binding residue
(residue number reindexed from 1)		C7 C10 H24 H30
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0005689 U12-type spliceosomal complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8y6o, PDBe:8y6o, PDBj:8y6o
PDBsum8y6o
PubMed38484052
UniProtQ9UDW3|ZMAT5_HUMAN Zinc finger matrin-type protein 5 (Gene Name=ZMAT5)

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