Structure of PDB 3jcs Chain V Binding Site BS02

Receptor Information
>3jcs Chain V (length=118) Species: 5661 (Leishmania donovani) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKSYTRPQFRRPHTYRKPAMAKPSNRVTVESKDIAAFSVIRYPLTTDKAM
KKIEENNTLTFIVDSRANKTEIKKAMRKLYQVKAVKVNTLIRPDGLKKAY
IRLSAAHDALDTANKIGL
Ligand information
>3jcs Chain 2 (length=1119) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cccaacugcagaccguacucaucaccgcaucagguccccaagcauagaau
gcucugguacauagagaaagguacacucagggaagucggcaaaauagaug
cguaaguucgcaagaagcauuggcucugagggcaauugccacucagaacu
gcuuacggcggggaauccaacuguauaauuaaaacauagguuugugaugc
auccaagugguguauaucgcaaacugauuucugcccagugcucugaaugu
caacgugacgagauucaccgacgcgcggguaaacggcgggagacucucuu
aagguagccaaaugccucgucuuccaauuagagacgcgcaugaauggauu
aaugagauucccucugucccgaguuacuaucuagcgaaacgacagucaag
ggaacggacuugaagggcuaagcggggaaagaagacccuguugaguuuga
cuccagucuggcucugugcggcgacaucugagguguaguauagguggaag
cgcaagcgcaaaugaaauaccaccacucggaaguugcuucacuuaucgaa
ugaagagaccaauggguuuagcguagucuggcuaugcaccgucuagguuu
gggaguaauuuuauggcggggugugcuugggcgugacucguggguaccca
accgugcuguaaacugaaccaacgggauugccucgugcaguuccgggucu
uguuucgagacaucugccagauggggaguuuggcugcggcuaucuguuac
acgacaacgcagguguccuaaggcgagcucagugggaacaaucucacgua
gaacacaagcguaaaagcuugcuugauuaacgauuuccaguacgaaucga
gacugcgaaagcaaggccagcgauccuuugcgaugaacaaaucauaccag
aggugucagaauaauuaccacagggauaacuggcuuguggcggccaagcg
auagcgacgucgcuuuuugauccuucgaugucggcucuuccuaaccuagc
gccgcagaagacgcuaaggguuggauuguucacccacugacagggaacgu
gagcuggguuuagaccgucgugagacagguugguuuuacccuacuuagcu
ggaaauugcgagaaaaaga
........................<<......>>......<<<<.....>
>>>........<<<<....<<<<.<<<<.<<...............<<<<
<.....<..>......>>>>><<.<<<<<<.<......>..>>>>>>.>>
..........<<<<<<<<<..<<<.........>>>..<<<<<<<....<
<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<.....<<
....<<<<......>>>>....>>..>>>>..>>>>>.............
......<...........<<<<<.......>>>>>.....>.....>>..
..>>.>>>>>>>.....>>.>>>>>>>>.>>>>............<<<<<
........>>>>>..<<<<<<<..<<<.<<......<<<<.<<<<<<..<
<<<<.<<<<<<<...<<<.<<<<<<.<<<.....................
............................>>>.>>>>>>.>>>...<<<<<
.....<<<.....<<.....<<<<<<<...>>>>>>>....>>.....<.
..<..................<<<<<<..>>>>>>...............
..>..>................<<<<<<<<.......>>>>>>>>..>>>
...>>>>>.......>>>>>>>..>>>>>..<<<....>>><<<<<<...
........>>>>>>..<<...<<<<<<<...<<<<<<....>>>>>>...
..<<......>>....>>>>>>>...<<..<<<<<<.......>>>>>>.
>>.<<<....>>>.>>........<<<<<<..<<<.......>>>..>>>
>>>.........>>>>..>>>>>>.......<<.<...<.<.<.....<.
...>.....>.>.>....>.>.>.......<<<<<.<<<<<<..<<<<<<
<.<......>.>>>>..>>>.<<<.........>>>.....>>>>>..>.
..>>>.>>....<<<<<<<....>>>.>>>>....>>..>>>.>>>>>>>
...................
Receptor-Ligand Complex Structure
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PDB3jcs 2.8- angstrom Cryo-EM Structure of the Large Ribosomal Subunit from the Eukaryotic Parasite Leishmania.
Resolution2.8 Å
Binding residue
(original residue number in PDB)
P33 Q34 N94 K95 K99 I117 K123
Binding residue
(residue number reindexed from 1)
P7 Q8 N68 K69 K73 I91 K97
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:3jcs, PDBe:3jcs, PDBj:3jcs
PDBsum3jcs
PubMed27373148
UniProtE9B8R9

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