Structure of PDB 6rxv Chain UU Binding Site BS02

Receptor Information
>6rxv Chain UU (length=902) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSAIFAPYRTIGLISPTGVPFTSIPLGKTTFQITTSVGRALQTYDLKRGL
NLVFVTRPQTPSDITATHAWKERVYAAFGDPRNGEPQGLWVFQRGKKVAE
LPLPSDLDQPIKQILIFGGWIVACALTRIEVWKAATLEHYTTIFPAASKK
GDNELTGGAINMPTFLNKIFVGRKDGWVEIWNVSTGKLIYTLLPPSPDCG
AVTCLQPTPALSLLAIAYSGGPLVIQNVLTDKTVLLLEAGTDDAPVTSIS
FRTDGLGAGQDGRKDGVMATATSVSGDVTFWDLNKGGRIMGVLRSAHNPP
SRHNIVRGGISKIEFLAGQPVIVTSGLDNSLKTWIFDESPFSPVPRILHQ
RSGHAAPVRCLHFLPSDFDGAEGGNKWLLSGGKDRSLWGWSLRRDGQSAE
LSQGAIRKKARKMGLLAGTTTLEDLKAPEITCIASSLNRDGGMGAIPGKQ
MIWDKNAELSGNTGWESVVTAHKDDPYARTWFWGRRRAGRWAFKTGDGEP
VSTVAISSCGTFALVGSTGGSIDMFNLQSGRHRQRFPSRFAPGTGRHTNA
VTGIVVDPLNRHVVSCSLDGKVKFWDFITGNLVDEIDWAPMTKIIGCRYH
PGNDLIAFACDDRSIRVVDIETKNTIREFWGCRGDINDFCFSPDGRWIVA
ASQDSIIRVWDLPTAHLIDAFRLEQPCTALAFSHTGEYLAGAMEGSLGVQ
IWTNRTLFRHVPTRQISESMMTLSLVPRSRWQTLLHIDIIKARNKPKEPP
KAPEKAPFFLPPVGQNGISSLIPQETFTSKLLVGGAKGDYTDFIEHLKAL
PPAAADLELRSLSIGNGDEATNELLHFIRALTSRLVARRDYELTQAWMTV
FLRLHFDLIMENEELLQALGEWREHQARERDRLSELVGYCGGVVSFLRSP
RT
Ligand information
>6rxv Chain C2 (length=230) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcgacaauacuucagagaaucauuucuauaguaguuguccucucuugug
uuuccuaaaggagccacagaucccacccggguugaugaacgagauccucg
gcgccagugagguccauuuacucucgcucuaccugcaaagguggcggucg
cgugccucgucucgcggcuguauagagaguggcgaugaucuguaccccgc
ggggugggugucgauggaagucugaccggc
..................................................
..........................<<<<......<.......<<<<<<
<<<<.<<............<<<<<<...<<<<<<....>>>>>><<<<<<
<<.<......>.>>>>>>>>....>>>>>>.........>>.<<<<<<..
>>>>>>.>>>>>>>.>>>...>...>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6rxv Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		S432 A435 R437 K438 R441 M478 R528 R530
Binding residue
(residue number reindexed from 1)		S402 A405 R407 K408 R411 M443 R485 R487
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006364 rRNA processing
Cellular Component
GO:0032040 small-subunit processome
GO:0034388 Pwp2p-containing subcomplex of 90S preribosome

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6rxv, PDBe:6rxv, PDBj:6rxv
PDBsum6rxv
PubMed31378463
UniProtG0S872

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