Structure of PDB 6zqc Chain UR Binding Site BS02

Receptor Information
>6zqc Chain UR (length=482) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPPDEEEQLLAKFVFGDTTDLQENLAKFNADFIEAAWIDSDDEKIKVPIL
VTNKTKKLRTSYNESKINGVHYINRLRSQFEKIYPRPKWVDDESDSNGDI
NALTKILSTTYNYKDTLSNSKLLPPKKLDIVRLKDANASHPSHSAIQSLS
FHPSKPLLLTGGYDKTLRIYHIDGKTNHLVTSLHLVGSPIQTCTFYTSLS
NQNQQNIFTAGRRRYMHSWDLSQTAKIEKFSRLYGHESTQRSFENFKVAH
LQNSQTNSVHGIVLLQGNNGWINILHSTSGLWLMGCKIEGVITDFCIDYQ
PISRGKFRTILIAVNAYGEVWEFDLNKNGHVIRRWKDQGGVGITKIQVGG
GTTTTCPALQISKIKQNRWLAVGSESGFVNLYDRNNAMTSSTPTPVAALD
QLTTTISNLQFSPDGQILCMASRAVKDALRLVHLPSCSVFSNWPTSGTPL
GKVTSVAFSPSGGLLAVGNEQGKVRLWKLNHY
Ligand information
>6zqc Chain D4 (length=230) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucgacguacuucauaggaucauuucuauaggaaucgucacucuuugacu
cuucaaaagagccacugaauccaacuugguugaugagucccauaaccuuu
guacccgugagaaauagcuugguccgcaauccuuagcgguucggccaucu
auaauuuugaauaaaaauugugccguugcuauggcgcgaugaucuaccca
uggguggguacaaauggcagucugacaagu
..................................................
.......................<<<<<.................<<<<<
<<<<<.<...<...<<<..<<<.<<<.<<<<......>>>>>>>>>>.>>
>.<<<<<......>>.>>>..<<<<<....>>>>>.>......>.<<<<.
.>>>>.>>>>>>>>.>>........>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zqc 90 S pre-ribosome transformation into the primordial 40 S subunit.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		K231 Q513 R542
Binding residue
(residue number reindexed from 1)		K126 Q401 R430
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0000292 RNA fragment catabolic process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:0034388 Pwp2p-containing subcomplex of 90S preribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6zqc, PDBe:6zqc, PDBj:6zqc
PDBsum6zqc
PubMed32943521
UniProtP40362|UTP18_YEAST U3 small nucleolar RNA-associated protein 18 (Gene Name=UTP18)

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