Structure of PDB 7aju Chain UQ Binding Site BS02

Receptor Information
>7aju Chain UQ (length=820) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QYKLSVVSGGKPALNNLSSVTGNKNIARLSQDQRNYIIPFNNQIKVYSVE
TRQCVKTLKFANNSLLSGIFLQEEENNESIVKILLGDITVPQQAHLITVF
TNNGHVIVLNYKGKLVESPKHFKISLADEKLANVFHSEGNYRILTTFKDN
SLQSYRLYALTFDDAKKQFEVAHQAEWHNVILSNISSNGKLLAHMCKDVS
TKDHEHKSISVVSLFDDSVNLSFPLGSILSSQTQSLSYNTRYVSSMAIDN
MGQQLAVGFASGVISIVSLADLQIRLLKWHIDSVLSLSFSHDGSYLLSGG
WEKVMSLWQLETNSQQFLPRLNGIIIDCQVLGPQGNYYSLILQMTENNSN
SDYQFLLLNASDLTSKLSINGPLPVFNSTIKHIQQPISAMNTKNSNSITS
LNHSKKKQSRKLIKSRRQDFTTNVEINPINKNLYFPHISAVQIFDFYKNE
QVNYQYLTSGVNNSMGKVRFELNLQDPIITDLKFTKDGQWMITYEIEYPP
NDLLSSKDLTHILKFWTKNDNETNWNLKTKVINPHGISVPITKILPSPRS
VNNSQGCLTADNNGGLKFWSFDSHESNWCLKKISLPNFNHFSNSVSLAWS
QDGSLIFHGFDDKLQILDFDTFKKFESLENTKTVSEFTLDSEIQTVKLIN
DTNLIVATRTTLNAINLLRGQVINSFDLYPFVNGVYKNGHMDRLITCDER
TGNIALVINQQLTDVPTINYKSRIIIFDSDLSTKLGNFTHHEYISWIGWN
YDTDFIFLDIESTLGVVGTNDEDEEDIALEFINGEKKDKLVNMNSFTSMF
DNIQNVQMDTFFDRVMKVLT
Ligand information
>7aju Chain D4 (length=223) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucgacguacuucaaggaucaucuauaggaaucgucacucuuugacucuu
cccacugaauccaacuugguugaugagucccauaaccuuuguaccccaga
gugagaaauagcuugguccgcaauccuuagcgguucggccaucuauaauu
uugaauaaaaauuuugccguugcuauggcgcgaugaucacccaugggugg
guacaaauggcagucugacaagu
..................................................
.............<<<<<.................<<<<<<<<<<<....
<........<<..<<<.<<<.<<<<......>>>>>>>>>>.>>..<<<<
<<....>>>.>>>..<<<<<....>>>>>........><<<<..>>>>>>
>>>>>>>.>>........>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7aju Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
Resolution3.8 Å
Binding residue
(original residue number in PDB)
N868 M869
Binding residue
(residue number reindexed from 1)
N792 M793
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0034511 U3 snoRNA binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0045943 positive regulation of transcription by RNA polymerase I
GO:2000234 positive regulation of rRNA processing
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005777 peroxisome
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:0033553 rDNA heterochromatin
GO:0034455 t-UTP complex
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7aju, PDBe:7aju, PDBj:7aju
PDBsum7aju
PubMed33326748
UniProtQ02931|UTP17_YEAST NET1-associated nuclear protein 1 (Gene Name=NAN1)

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