Structure of PDB 7ajt Chain UK Binding Site BS02

Receptor Information
>7ajt Chain UK (length=242) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKLVHDVQKKQHRERSQLTSRSRYGFLEKHKDYVKRAQDFHRKQSTLKVL
REKAKERNPDEYYHAMHSRKTDAKGLLISSRHGDEEDESLSMDQVKLLKT
QDSNYVRTLRQIELKKLEKGAKQLMFKSSGNHTIFVDSREKMNEFTPEKF
FNTTSEMVNRSENRLTKDQLANASSIMPKESLDKKKLKKFKQVKQHLQRE
TQLKQVQQRMDAQRELLKKGSKKKIVDSSGKISFKWKKQRKR
Ligand information
>7ajt Chain D3 (length=1327) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aagauaguuaucugguugauccugccagucauaugcuugucucaaagauu
aagccaugcaugucuaaguauaagcaauuuauacagugaaacugcgaaug
gcucauuaaaucaguuaucguuuauuugauagcaugguauaacuguggua
auucuagagcuaauacaugcuaucucgacccuuuggaagagauuauuuau
uagauucuucggacucuugaugauucauaauaacuuuucgaaucgcaugg
ccuugugcuggcgaugguucauucaaauuucugcccuaucaacuuucgau
gguaggauaguggccuaccaugguuucaacggguaacggggaauaagggu
ucgauuccggagagggagccugagaaacggcuaccacauccaaggaaggc
agcaggcgcgcaaauuacccaauccuaauucagggagguagugacaauaa
auaacgauacagggcccauucgggucuuguaauuggaaugaguacaaugu
aaauaccuuaacgaggaacaauuggagggcaagucuggugccagcagccg
cgguaauuccagcuccaauagcguauauugcucguaguugaacuuugggc
ccgguuggccggucggauuuccaacggggccuuuuuacuuugaaaaaauu
agaguguucaaagcaggcguauugcucgauauauuagcauggaauaauag
gacguuugguucuauuuuguugguuucuaggaccaucguaauuaauaggg
acggucgggggcaucaguauucaauugucagaggugaaauucuuggauuu
auugaagacuaacuacugcgaaagcauuugccaaggacguuuucauuaau
caagaacgaaacuaugccgacuagggaucgggugguguuuuuuuaaugac
ccacucggcaccuuacgaggaguauggucgcaaggcugaaacuuaaagga
auugacggaagggcaccaccaggaguggagccugcggaaacucaccaggu
ccagacacaauauuugugggugguggugcaugugaugcccuuguucuggc
gcgcgcuacacugacggagccagcgagucuaaccuuggccgagaggucuu
gguaaaaacuccgucggggaacgaggaauuccuaguaagcgcaagucauc
agcuugcguugauuacgucccugcccuuuguacacaccgcccgucgcuag
uaccgauugaauggcuuagugaggccucaggaucugcuuagagaaggggg
caacuccaucucagagcggaaauuuggacaaacuuggucauuuagaggaa
cuaaguuuccguaggugaaccugcgga
...........................<<.<<<<<<...<.<........
..<<<.<<<..<<....<<....<<..........>>...>>.>>.....
.<<..<.....<<<..<<..<<....<<<.......<<....<<.<<<..
...>>>.>>.....>>.....<<<<<..<<....>>..>>>>>...<<<<
<<...<<....>>....<<......>>>>>>>>.........<<<<..<<
<.....>>>.>>>>....>>>...>>>>..>>>.<<<.....<......<
<<<<<<.......>>>>>>>..>.......>>>...<<<.<<<......>
>>....>>>>>>.<<.<<<<........>>>>.>>.<.<......>.>..
.>>>>>>.........<<<....<<<.....>>>..>>>.......>.>.
....<<<<<<<.<<<<<....>>>>>.>>>.>>>>......<<..<....
.......>..>>.........<<<<<<.......<<<....>>>......
............>>>>>>..>>>>>>>>.<.<<...<<<.<<....<<<<
<<.<<<<<............>>>>>.>>>>>>..<<<<<.<<........
...<<.......>>..<<.....>>............>>.>>..>>>...
.<<<....<..<<...............>>..>...>>>..>>....<<<
<<<.<<...<<<<..<<..<<<<<<.<...<<<......>>>......>.
>>>>>>..>>.......<<....>>...>>>>...>>>>>.>>>...>>>
...>>.>..........<<...<<<..<<<<<<<<.<<<........>>>
>>>>>>>>..>>>..>>..................<<.........>>..
...<<<<<<<<<<<<..<<.<<<<<...<<<.<<<<........<<<<<.
.....<<<<<...>>>>>......<<...........>>.....>>>>>>
>>>.>>>.....<<<<<<<............<<<..<<<<....>>>>..
>>>.....>>>>>>>.............>>>>>....<<<<<<<<.....
..>>>>>>>>......>>...>>>>>>>............>>>>>..<<<
<.<<....<<<<<<<<.<<...<.<<......<<<<<<<....<.<.<..
....>.>.>....>>>>>>>.....>>.>...>>.>>>>>>>>...>>.>
>>>....<<<<<<<<....>>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ajt Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
Resolution4.6 Å
Binding residue
(original residue number in PDB)		V8 Q9 K10 K11 Q12 H13 R14 E15 R16 Y25 K30 H31 Y34 F41 H42
Binding residue
(residue number reindexed from 1)		V7 Q8 K9 K10 Q11 H12 R13 E14 R15 Y24 K29 H30 Y33 F40 H41
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0006412 translation
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005732 sno(s)RNA-containing ribonucleoprotein complex
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7ajt, PDBe:7ajt, PDBj:7ajt
PDBsum7ajt
PubMed33326748
UniProtP34247|UTP11_YEAST U3 small nucleolar RNA-associated protein 11 (Gene Name=UTP11)

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