Structure of PDB 6rxt Chain UA Binding Site BS02

Receptor Information
>6rxt Chain UA (length=839) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKTNFKFSNLLGTVYCRGNLLFSPDGTHLFSPVGNRVTVFNLVENKSYTF
PFAHRKNISRIGLTPQGNLLLSIDEDGQAILTNVPRRVVLYHFSFKSPVT
ALAFSPSGRHFVVGLKRKIEVWHVPSTPDTNEDGDLEFAPFVRHHTHMQH
FDDVRHLEWSSDSRFFLSASKDLTARIWSLDTEEGFVPTVLSGHRQGVVG
AYFSKDQETIYTVSKDGAVFEWKYVAKPGHEDMQWRIVNKHFFMQNAATL
RCAAYHAESNLLVAGFSNGIFGLYEMPDFNLIHTLSISQNEIDFVTINKS
GEWLAFGASKLGQLLVWEWQSESYILKQQGHFDAMNSLVYSPDGQRIVTA
ADDGKIKVWDVESGFCIVTFTEHTSGVTACEFAKKGSVLFTASLDGSVRA
WDLIRYRNFRTFTAPERLSFTCMAVDPSGEVIAAGSIDSFDIHIWSVQTG
QLLDRLSGHEGPVSSLAFAPDGSVLVSGSWDRTARIWSIFSRTQTSEPLQ
LQSDVLDVAFRPDSKQIAISTLDGQLTFWSVSEAQQVSGVDGRRDVSGGR
RITDRRTAANVAGTKNFNTIRYSMDGTCLLAGGNSKYICLYSTTTMVLLK
KFTVSVNLSLSGTQEFLNSKLMTEAGPVGLLDDQGEASDLEDRIDRSLPG
SKRGDPGARKKFPEVRVSGVAFSPTGNSFCAASTEGLLVYSLDNTVQFDP
FDLNMEITPASTLAVLEKEKDYLKALVMAFRLNEAGLITRVYQAIPYTDI
GLVVEQFPTVYVPRLLRFVAAQTEQSPHMEFCLLWIRALIDKHGPWLAAN
RGKVDVELRVVARAVAKMRDEIRRLADENVYMVDYLLNQ
Ligand information
>6rxt Chain C2 (length=230) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcgacaauacuucagagaaucauuucuauaguaguuguccucucuugug
uuuccuaaaggagccacagaucccacccggguugaugaacgagauccucg
gcgccagugagguccauuuacucucgcucuaccugcaaagguggcggucg
cgugccucgucucgcggcuguauagagaguggcgaugaucuguaccccgc
ggggugggugucgauggaagucugaccggc
..................................................
..........................<<<<......<.......<<<<<<
<<<<.<<............<<<<<<...<<<<<<....>>>>>><<<<<<
<<.<......>.>>>>>>>>....>>>>>>.........>>.<<<<<<..
>>>>>>.>>>>>>>.>>>...>...>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6rxt Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Resolution7.0 Å
Binding residue
(original residue number in PDB)		R558 R564 T565 N568 F624 L625 N626 S627 M630
Binding residue
(residue number reindexed from 1)		R550 R556 T557 N560 F616 L617 N618 S619 M622
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005730 nucleolus
GO:0032040 small-subunit processome
GO:0034388 Pwp2p-containing subcomplex of 90S preribosome

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6rxt, PDBe:6rxt, PDBj:6rxt
PDBsum6rxt
PubMed31378463
UniProtG0SF93

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