Structure of PDB 5c6h Chain U Binding Site BS02

Receptor Information
>5c6h Chain U (length=151) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGV
QRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISF
GAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFH
V
Ligand information
>5c6h Chain V (length=23) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GVMTQEVGQLLQDMGDDVYQQYR
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5c6h Structure of Mcl-1 complexed with Mule at 2.05 Angstroms resolution
Resolution2.05 Å
Binding residue
(original residue number in PDB)		H224 F228 M231 K234 L235 S245 R248 V249 V253 D256 N260 G262 R263 F318 F319
Binding residue
(residue number reindexed from 1)		H54 F58 M61 K64 L65 S75 R78 V79 V83 D86 N90 G92 R93 F148 F149
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

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Biological Process
External links
PDB RCSB:5c6h, PDBe:5c6h, PDBj:5c6h
PDBsum5c6h
PubMed
UniProtQ07820|MCL1_HUMAN Induced myeloid leukemia cell differentiation protein Mcl-1 (Gene Name=MCL1)

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