Structure of PDB 1nji Chain U Binding Site BS02

Receptor Information

>1nji Chain U (length=119) Species: 2238 (Haloarcula marismortui)

SKQPDKQRKSQRRAPLHERHKQVRATLSADLREEYGQRNVRVNAGDTVEV
LRGDFAGEEGEVINVDLDKAVIHVEDVTLEKTDGEEVPRPLDTSNVRVTD
LDLEDEKREARLESEDDSA

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 1nji Chain U Residue 8073

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1nji Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit
• Resolution: 3.0 Å
• Binding residue (original residue number in PDB): Q37 R111 L112 S114 D117
• Binding residue (residue number reindexed from 1): Q37 R111 L112 S114 D117
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation
• GO:0042273 ribosomal large subunit biogenesis

Cellular Component

• GO:0005840 ribosome
• GO:0015934 large ribosomal subunit
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:1nji, PDBe:1nji, PDBj:1nji
• PDBsum: 1nji
• PubMed: 12860128
• UniProt: P10972|RL24_HALMA Large ribosomal subunit protein uL24 (Gene Name=rpl24)