Structure of PDB 7r81 Chain T1 Binding Site BS02

Receptor Information
>7r81 Chain T1 (length=191) Species: 5141 (Neurospora crassa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VNLRTQKRLASSVLGVGQRKIWLDPNEVSEISNANSRQTIRKLVADGLII
KKPVTMHSRSRARELNLARRIGRHRGFGKRKGTADARMPEQVLWMRRQRV
LRRLLVKYRASGKIDKHLYHELYHLAKGNTFKHKRALVEHIHRAKAEKAR
EKAIKEEMDAKRARTKAARERKLERQAAKRNALAGEEEESK
Ligand information
>7r81 Chain A2 (length=1769) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauucugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguuuaagcaauuaaaccgcgaaacugcgaauggcucau
uaaaucaguuauaguuuauuugauaguaccuuacuacauggauaaccgug
guaauucuagagcuaauacaugcuaaaaaccccgacuucagggguguauu
uauuagauuaaaaaccaaugcccuucggggcuaacuggugauucauaaua
acuucucgaaucgcauggccuugcgcuggcgaugguucauucaaauuucu
gcccuaucaacuuucgacggcugggucuuggccagccauggugacaacgg
guaacggaggguuagggcucgaccccggagaaggagccugagaaacggcu
acuacauccaaggaaggcagcaggcgcgcaaauuacccaaucccgacacg
gggagguagugacaauaaauacugauacagggcucuuuugggucuuguaa
uuggaaugaguacaauuuaaaucccuuaacgaggaacaauuggagggcaa
gucuggugccagcagccgcgguaauuccagcuccaauagcguauauuaaa
guuguugagguuaaaaagcucguaguugaaccuugggcucggcccgucgg
uccugggucgggccuuuccuggagaaccgcaugcccuucacugggugugu
cggggaaccaggacuuuuaccgugaacaaaucagaucgcucaaagaaggc
cuaugcucgaauguacuagcauggaauaauagaauaggacgugugguucu
auuuuguugguuucuaggaccgccguaaugauuaauagggacagucgggg
gcaucaguauucaauugucagaggugaaauucuuggauuuauugaagacu
aacuacugcgaaagcauuugccaaggauguuuucauuaaucaggaacgaa
aguuaggggaucgaagacgaucagauaccgucguagucuuaaccauaaac
uaugccgauuagggaucggacgguguuauuuuuugacccguucggcaccu
uacgauaaaucaaaauguuugggcuccugggggaguauggucgcaaggcu
gaaacuuaaagaaauugacggaagggcaccaccagggguggagccugcgg
cuuaauuugacucaacacggggaaacucaccagguccagacacgaugagg
auugacagauugagagcucuuucuugauuucgugggugguggugcauggc
cguucuuaguugguggagugauuugucugcuuaauugcgauaacgaacga
gaccuuaaccugcuaaauagcccguauugcuuuggcaguacgcuggcuuc
uuagagggacuaucggcucaagccgauggaaguuugaggcaauaacaggu
cugugaugcccuuagauguucugggccgcacgcgcgcuacacugacacag
ccagcgaguacucccuuggccggaagguccggguaaucuuguuaaacugu
gucgugcuggggauagagcauugcaauuauugcucuucaacgaggaaucc
cuaguaagcgcaagucaucagcuugcguugauuacgucccugcccuuugu
acacaccgcccgucgcuacuaccgauugaauggcucagugaggcuuccgg
acuggcccagggaggucggcaacgaccacccagggccggaaagcuaucca
aacucggucauuuagaggaaguaaaagucguaacaaggucuccguuggug
aaccagcggagggaucauu
...<<<<<.[.((((>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<<...<<.........>>..>>>.>>......<<...
.....<<<..<<..<<....<<<...............<<.....<..<<
<.....>>>..>......>>........<<<<<.......>>>>><...<
<<<<<......[.......<<<<....>>>>..............>>>>>
>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>>..>>
>.<<<....<<<......<<<<<<.......>>>>>>..>>>......>>
>...<<<.<<<<....>>>>....>>>.>>.<<.<<<..........>>>
.>>.<.<<<..>>>.>...>>>>>>.........<<<....<<<<...>>
>>..>>>..>....>.>....<<<<.<<<<<<..........>>>>>>..
>>>>.....<<..<...........>..>>.........<<<<<((....
..<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>>>..
.......<<<((.....<.<<...<<<.<<....<<<<<<<<<<<<....
...>>>>>>>>>>>>..<<<..............................
.........>>>....<<<<<<<<.......<<..<<.......>>.<<<
....>>>....>>......>>>>>..>>>.........<<<.<<<<<<<<
<...........].>>>>>>>>>>>>.....>>....<<<<<<.<<...<
<<<..<<..<<<<<<.<...<<<......>>>......>.>>>>>>..>>
.......<<....>>...>>>>...>>>>>.>>>...>>>...>>.>...
.<<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>.......
...<<<.<<.<<<..<<<<<<<<.<<<<.....>>>>>>>>>>>>..>>>
...<<..))>>...>>.....>>>.>>>.<<<......<<<<....>>>>
....>>>..)))).]<<<<<.<<<<<<<..<<.<<<<<<..<<<..<<<.
.......<<........>>..........<<<<<<.....<<<<<.....
...<<.<<<........>>>.>>......>>>>>...<<.<<<..<<.<<
<<<<....<<<.<<<<<....>>>...<<<......>>>...>>.>>>..
..<<<<<.<<..<<<<..<<<<..<<<..........>>>....>>>>..
>>>>.>>....<<<<<<....>>>>>>.......>>>>>....>>>.>>>
.....>>>>>>>.....>>>.>>>......>>>..>>>.....<<<<<<<
......<<.....<<<.<<<<....>>>>.>>>....>>.......>>>>
>>>......<....<<<<<<..........>>>>>>....>.....>>>>
>>....<<<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>
.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<.<..<..
.<<<<<<<.<<<.<<<<<....>>>>>.>>>.>>>>>>>...>..>.>>.
.>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<<.
.>>>>>>>>>>........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7r81 Structure of the translating Neurospora ribosome arrested by cycloheximide
Resolution2.7 Å
Binding residue
(original residue number in PDB)		M159 K162 R163 R165 R170 R172 R176
Binding residue
(residue number reindexed from 1)		M158 K161 R162 R164 R169 R171 R175
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7r81, PDBe:7r81, PDBj:7r81
PDBsum7r81
PubMed34815343
UniProtQ7S5N9

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