Structure of PDB 8ipx Chain T Binding Site BS02

Receptor Information

>8ipx Chain T (length=124) Species: 9606 (Homo sapiens)

PLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAVGIV
VNKQVKGKILAKRINVRIEHIKHSKSRDSFLKRVKENDQKKKEAKEVQLK
RQPAPPREAHFVRTNGKEPELLEP

Ligand information

>8ipx Chain 3 (length=115)

gucuacggccauaccacccugaacgcgcccgaucucgucugaucucggaa
gcuaagcagggucgggccugguuaguacuuggaugggaccgccuggaaua
ccgggugcuguaggc

<<<<<<<<<....<<<<<<<<.....<<<<<..............>>>..
>>....>>>>>>.>><<<<<<.......<.<<.<<<..>>>>>.>.....
>>>>>>>>>>>>>>>

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8ipx Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
• Resolution: 4.3 Å
• Binding residue (original residue number in PDB): P26 L27 A28
• Binding residue (residue number reindexed from 1): P1 L2 A3

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0005515 protein binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005783 endoplasmic reticulum
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0016020 membrane
• GO:0022625 cytosolic large ribosomal subunit
• GO:0022626 cytosolic ribosome
• GO:0045202 synapse
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8ipx, PDBe:8ipx, PDBj:8ipx
• PDBsum: 8ipx
• PubMed: 37491604
• UniProt: P46778|RL21_HUMAN Large ribosomal subunit protein eL21 (Gene Name=RPL21)