Structure of PDB 8a98 Chain T Binding Site BS02

Receptor Information
>8a98 Chain T (length=153) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HYSRKPQVSSKSAKAKVSDLRCHYKNTFETANVINGMPLRKAQQLYRQVL
AKTRCIPFKRYNGKIGRTAQAKEWGQTKGRWPRKSVVAMMSLLKNAEANA
IEKGLDPNQMVIKHVQVDQAARMRRRTYRAHGRITPYMCSPCHVQLFMSE
KKE
Ligand information
>8a98 Chain 2 (length=1047) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccaacugcagaccguacucaucaccgcaucagguccccaagcauagaaug
cucugguacauagagaaagguaaacucagggaagucggcaaaauagaugc
guaaguucgcaagaagcauuggcucugagggcaacacaaauugccaacuc
agaacugcuuacggcggggaauccaacuguauaauuaaaacauagguuug
ugaugcauccaagugguguauaucgcaaacugauuucugcccagugcucu
gaaugucaacgugacgagauucaccgacgcgcggguaaacggcgggagua
auaugacucucuuaagguagccaaaugccucgucuuccaauuagagacgc
gcaugaauggauuaaugagauucccucugucccgaguuacuaucuagcga
aacgacagucaagggaacggacuugaagggcuaagcggggaaagaagacc
cuguugaguuugacuccagucuggcucugugcggcgacauguugcuucac
uuaucgaaugaagagaccaaugggauuagcguagucuucgggcuaugcac
cgucuagguuccaaccgugcuguaaacugaaccaacgggauccggagucu
uguuucgagacaucugccagauggggaguuuggcuggggcggcauaucug
uuacacgacaacgcagguguccuaaggcgagcucagugggaaaucucacg
uagaacacaagcguaaaagcuugcuugauuaacgauuuccaguacgaauc
gagacugcgaaagcaaggccagcgauccuuugcgaugaacaaaucauacc
agaggugucagaauaauuaccacagggauaacuggcuuuggcggccaagu
cgcugauccuucgaugucggcucuuccuaaccuagcgcgacgcuaagggu
uggauuguucacccacugacagggaacgugagcuggguuuagaccgucgu
gagacagguugguuuuacccuacuuagcuggaaauugcgagaaaaagauu
auccgugcaaagcggagcgguggguaguacuugguacgcucaucacc
.......................<<......>>......<<<<<...>>>
>>........<<<<....<<<<.<<<<.<<.........<.....<<<<<
....<<..>>.....>>>>><<.<<<<<<<<<<<......>>>>>..>>>
>>>.>>..........<<<<<<<<<..<<<.........>>>..<<<<<<
<....<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<.
<...<<....<<<<......>>>>....>>.>>>>>..>>>>>....<..
.......>...........<...........<<<<<.......>>>>>..
...>.....>>....>>.>>>>>>>..>..>>.>>>>>>>>.>>>>....
........<<<<<........>>>>>..<<<<<<<..<<<.<<......<
<<<.<<<<<<..<<<<<.<<<<<<<...<<<.<<<<<<..>>>>>>.>>>
...<<<<<.....<<<<....<<.....<<<<<<<<<..>>>>>>>>>.>
>.....<<<<..>>>>...................<<<...>>>..>>>>
...>>>>>.......>>>>>>>..>>>>>...<<<.....>>>..<<<<<
<...........>>>>>>..<<...<<<<<<<...<<<<<<..>>>>>>.
....<<......>>....>>>>>>>...<<...<<<<<.......>>>>>
..>>.<<<....>>>.>>.........<<<<<..<<<.......>>>..>
>>>>..........>>>>..>>>>>>.......<<.<......<......
>...>..>>.......<<<<<.<<<<<<..<<<<<<<...>>>>..>>>.
<<<.........>>>.....>>>>>..>...>>>.>>....<<<<<<<..
..>>>.>>>>....>>..>>>.>>>>>>>.....................
.<.<.......>.>..<.<<<<<<<.<<<<...>>>>>>>>>>>.>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8a98 CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : snoRNA MUTANT
Resolution2.46 Å
Binding residue
(original residue number in PDB)		H25 K66 G68 R69 K80 R82 W83 P84 R85 K86 R127 Y130 G134 I136 T137 P138 Y139 M140
Binding residue
(residue number reindexed from 1)		H23 K64 G66 R67 K78 R80 W81 P82 R83 K84 R125 Y128 G132 I134 T135 P136 Y137 M138
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8a98, PDBe:8a98, PDBj:8a98
PDBsum8a98
PubMed38722744
UniProtQ4QAX6

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