Structure of PDB 6tqo Chain T Binding Site BS02

Receptor Information
>6tqo Chain T (length=255) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MHPMLNIAVRAARKAGNLIAKNYETPDANDFVTNVDKAAEAVIIDTIRKS
YPQHTIITEESGELEGTDQDVQWVIDPLDGTTNFIKRLPHFAVSIAVRIK
GRTEVAVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFP
FKAKQYATTYINIVGKLFNECADFRRTGSAALDLAYVAAGRVDGFFEIGL
RPWDFAAGELLVREAGGIVSDFTGGHNYMLTGNIVAGNPRVVKAMLANMR
DELSD
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6tqo Chain T Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6tqo Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		E67 D84 L86
Binding residue
(residue number reindexed from 1)		E59 D76 L78
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.25: inositol-phosphate phosphatase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0001072 transcription antitermination factor activity, RNA binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008934 inositol monophosphate 1-phosphatase activity
GO:0016787 hydrolase activity
GO:0031403 lithium ion binding
GO:0042134 rRNA primary transcript binding
GO:0046872 metal ion binding
GO:0047954 glycerol-2-phosphatase activity
GO:0052832 inositol monophosphate 3-phosphatase activity
GO:0052833 inositol monophosphate 4-phosphatase activity
Biological Process
GO:0006020 inositol metabolic process
GO:0007165 signal transduction
GO:0031564 transcription antitermination
GO:0042254 ribosome biogenesis
GO:0046854 phosphatidylinositol phosphate biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6tqo, PDBe:6tqo, PDBj:6tqo
PDBsum6tqo
PubMed32871103
UniProtP0ADG4|SUHB_ECOLI Nus factor SuhB (Gene Name=suhB)

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