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BioLiP

Structure of PDB 5ylz Chain T Binding Site BS02

Receptor Information
>5ylz Chain T (length=344) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FTKSELKRRRKTRKGDGPWGSWSSEQIEVEEVSHFYQGRGYLYPPNDVDV
DLREERISFRCYLPKKVIRNYPGHPEGTTALKFLPKTGHLILSGGNDHTI
KIWDFYHDYECLRDFQGHNKPIKALRFTEDCQSFLSSSFDRSVKIWDTET
GKVKTRLHLNSTPADVESRPTHEFIVGLSNSKILHYDLVQTYDHHLSSIL
ALKYFPDGSKFISSSEDKTVRIWENQINVPIKQISDHSMPFLNVHPSQNY
FCAQSMDNRIYSFSLKPKYKRHPKKIFKGHSSGISLAFSGDGRYICSGDS
KSRLFTWDWNTSRLLNNIKIPGPITQVETSKVICSGAAGKIYVC
Ligand information
>5ylz Chain E (length=62) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auaaauuuuuaagguauguauuuauuuuuuuuaagaacuagauacuaaca
caaauaguaaau
..................................................
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Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ylz Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae
Resolution3.6 Å
Binding residue
(original residue number in PDB)		K375 T414
Binding residue
(residue number reindexed from 1)		K275 T311
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000386 second spliceosomal transesterification activity
GO:0003729 mRNA binding
GO:0005515 protein binding
Biological Process
GO:0000348 mRNA branch site recognition
GO:0000350 generation of catalytic spliceosome for second transesterification step
GO:0000389 mRNA 3'-splice site recognition
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0034399 nuclear periphery
GO:0071013 catalytic step 2 spliceosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ylz, PDBe:5ylz, PDBj:5ylz
PDBsum5ylz
PubMed29153833
UniProtP40968|PRP17_YEAST Pre-mRNA-processing factor 17 (Gene Name=CDC40)

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