Structure of PDB 7zjx Chain SZ Binding Site BS02

Receptor Information
>7zjx Chain SZ (length=136) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKAD
RDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSA
LRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL
Ligand information
>7zjx Chain S2 (length=1770) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucguacuuggauaacugugguaa
uucuagagcuaauacaugccgacgggcgcugacccccuucgcggggggga
ugcgugcauuuaucagaucaaaaccaacccggugccggcggcuuugguga
cucuagauaaccucgggccgaucgcacgcccuccguggcggcgacgaccc
auucgaacgucugcccuaucaacuuucgaugguagucgccgugccuacca
uggugaccacgggugacggggaaucaggguucgauuccggagagggagcc
ugagaaacggcuaccacauccaaggaaggcagcaggcgcgcaaauuaccc
acucccgacccggggagguagugacgaaaaauaacaauacaggacucuuu
cgaggcccuguaauuggaaugaguccacuuuaaauccuuuaacgaggauc
cauuggagggcaagucuggugccagcagccgcgguaauuccagcuccaau
agcguauauuaaaguugcugcaguuaaaaagcucguaguuggaucuuggg
agcgggcggccgcccguccccgccucucggcgccccggggcccgaagcgu
uuacuuugaaaaaauuagaguguucaaagcaggcccgagccgccuggaua
ccgcagcuaggaauaauggaauaggaccgcgguucuauuuuguugguuuu
cggaacugaggccaugauuaagagggacggccgggggcauucguauugcg
ccgcuagaggugaaauucuuggaccggcgcaagacggaccagagcgaaag
cauuugccaagaauguuuucauuaaucaagaacgaaagucggagguucga
agacgaucagauaccgucguaguuccgaccauaaacgaugccgacuggcg
augcggcggcguuauucccaugacccgccgggcagcuuccgggaaaccaa
agucuuuggguuccggggggaguaugguugcaaagcugaaacuuaaagga
auugacggaagggcaccaccaggaguggagccugcggcuuaauuugacuc
aacacgggaaaccucacccggcccggacacggacaggauugacagauuga
uagcucuuucucgauuccgugggugguggugcauggccguucuuaguugg
uggagcgauuugucugguuaauuccgauaacgaacgagacucuggcaugc
uaacuaguuacgcgacccccgagcggucggcgucccccaacuucuuagag
ggacaaguggcguucagccacccgagauugagcaauaacaggucugugau
gcccuuagauguccggggcugcacgcgcgcuacacugacuggcucagcgu
gugccuacccuacgccggcaggcgcggguaacccguugaaccccauucgu
gauggggaucggggauugcaauuauuccccaugaacgaggaauucccagu
aagugcgggucauaagcuugcguugauuaagucccugcccuuuguacaca
ccgcccgucgcuacuaccgauuggaugguuuagugaggcccucggaucgg
ccccgccggggucggcccacggcccuggcggagcgcugagaagacggucg
aacuugacuaucuagaggaaguaaaagucguaacaagguuuccguaggug
aaccugcggaaggaucauua
...<<<<<...[[[[>>>>>[[[.((((((.....{{.........[[[.
[[[..<<....<<....<<..........>>...>>.>>......{{...
.....[[[......{{....[[[[[.........<<.....<<.<<<...
..>>>.>>......>>.........<<<<...<<<<<<....>>>>>>..
.>>>>[[..(((((.....<<<<<<<<.<<<....>>>.......<....
..>..)))))......]]...<<<<.<<<<......>>>>>>>>.]].]]
]...}}....]]].<<<....<<<....<<<<<<<.........>>>>>>
>>>>......>>>...<<<.<<<<....>>>>....>>>.}}.<<.<<<.
.........>>>.>>.<.<<....>>.>...]]]]]].........<<<.
...<<<<...>>>>..>>>......}}.......<<<<<<<<<.<<<...
.>>>..>>>>>>.>>>......<<..<...........>..>>.......
..<<<<<((......<<<<.....<<..))>>.......>>>>.>>>>>.
.)))))).]]]............{{.......{{...[[[.[[.....<<
.<<<<<<....>>>>>>.>>.<<...<<<<..<<.<>>>..>>>>.>>..
<<<<<<.<.......<<...<.......>.<<<<.......>>>>...>>
......>.>>>..>>>........{.[[.(((((((......>>>>>>>>
.))))))).]].}....]]....<<<<<<..<...<<<<..<<..<<<<<
<<<...<<<......>>>......>>>>>>>>..>>.......<<....>
>...>>>>..>..>>>.>>>...]]]...}}......<<<<<<<...<..
.<<<<.<.....>.>>>>...>>>>>>>>..........<<<.<<.<<<.
.<.<<<<<<.<<<<<....>>>>>>>>>>>.>..>>>...<<..}}>>..
.>>.....>>>.....<<<......<<<......>>>....>>>..]]]]
..<<<<<.<<<<<<<..<<..<<<<<..<<<.<<<<<.......<<....
....>>..........<<<<<......<<<<<<.......<<.<<<....
....>>>.>>.....>>>>>>...<<.<<<..<<.<<<<<<....<<<.<
<<<<....>>>...<<<......>>>...>>.>>>....<<<...<...<
<<<..<<<<<<<<<<<<.......>>>>.>>>>.....>>>>..>>>>..
>.....<<<<<.....>>>>>........>>>....>>>.>>>.....>>
>>>>>.......>>>>>....>.>>>>.>>>.....<<.<<<........
<.......<<<.<<<<....>>>>.>>>....>.........>>>.>>..
..........<<<<<..........>>>>>...........>>>>>....
.<<<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>..
..<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<.<<...<<<<
<<<<<<<<<<<<<<.....>>>>>>>>>>>>.>.>>>>>...>>.>>>>.
.>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<<.
.>>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7zjx Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		N38 D39 F41 H43 S48 G49 K50 E51 T52 R55 T57 G59 M60 D65 R66 E68 R98 I135 P136 S137 D138 T140 R141 K143 G144 G145 R146 R147 R149 R150
Binding residue
(residue number reindexed from 1)		N23 D24 F26 H28 S33 G34 K35 E36 T37 R40 T42 G44 M45 D50 R51 E53 R83 I120 P121 S122 D123 T125 R126 K128 G129 G130 R131 R132 R134 R135
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7zjx, PDBe:7zjx, PDBj:7zjx
PDBsum7zjx
PubMed35709277
UniProtA0A7L0BEC6

[Back to BioLiP]