Structure of PDB 8rxx Chain ST Binding Site BS02

Receptor Information
>8rxx Chain ST (length=142) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VRMHGNGRGKASSALPYRRTPPAWLKIASRNVVKMVCKSSRKGMMPSQIG
MELRDSMGIAQVKNVTGRKILRILKHNGLAPEIPEDLYFLVKRATQMRKH
LERHTTDRDTKYRLILVESRIHRLARYYKRVKQLPPTWKYES
Ligand information
>8rxx Chain L3 (length=183) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agugguaaugcgaaacacuugccagguaacaaaucaauccucccacggug
agcuuucuuuucaccauaauccaccuugggccuuuuuacuuucgcguugu
ucggagcgggggcucaagauugaaaaaugcagcucuuacugucauuugug
aguucugcgcauuaaagcaaaaaccuggggugu
.<<......>>.....<<<..<<<<<<.......<<...<<<....<<<<
<<.......>>>>>><...<<.<.<<<<<<<<<<<.......<<......
.>>....>>>>>>>>>>>.>.>>....><..<..........>..>...>
>>...>>...............>>>>>>>>>..
Receptor-Ligand Complex Structure
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PDB8rxx Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
Resolution2.97 Å
Binding residue
(original residue number in PDB)		W139 K140
Binding residue
(residue number reindexed from 1)		W138 K139
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0070181 small ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0035869 ciliary transition zone
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8rxx, PDBe:8rxx, PDBj:8rxx
PDBsum8rxx
PubMed38722744
UniProtQ4Q3M1

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