Structure of PDB 5wlc Chain ST Binding Site BS02

Receptor Information
>5wlc Chain ST (length=599) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QLKNLKAALKAREKKKAIAEIREEFNPFEIKAARNKRIAVGKPGISKQIG
EEQRKRAFEARKMMKNKRGGVIDKRAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAKEKLGKFTAVLLRHIIFLSNQNYLKNVQSFKRT
QNALISILKSLSEKYNRELSEECRDYINEMQARYKKNHFDALSNGDLVFF
SIIGILFSTSDQYHLVITPALILMSQFLEQIKFNSLKRIAFGAVLVRIVS
QYQRISKRYIPEVVYFFQKILLTFIVEPLDFENIRLDSYELGLPLDVDFT
KKRSTIIPLHTLSTMDTEAHPVDQCVSVLLNVMESLDATISTVWKSLPAF
NEIILPIQQLLSAYTSKYSDFEKPRNILNKVEKLTKFTEHIPLALQNHKP
VSIPTHAPKYEENFNPDKKSYDPDRTRSEINKMKAQLKKERKFTMKEIRK
DAKFEARQRIEEKNKESSDYHAKMAHIVNTINTEEGAEKNKYERERKLR
Ligand information
>5wlc Chain L2 (length=169) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucgacguacuucauaggaucauuucuauaggaaucgucacucuuugacu
cuucaaaagagccacugaauccaacuugguugaugagucccauaaccuuu
guacccagugagaaaccguauggcgcgaugaucuacccauggguggguac
aaauggcagucugacaagu
..................................................
.......................<<<<<.................<<<<<
<<<<<.<<.......<<<..>>>.........>><<<<..>>>>.>>>>>
>>>.>>........>>>>>
Receptor-Ligand Complex Structure
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PDB5wlc The complete structure of the small-subunit processome.
Resolution3.8 Å
Binding residue
(original residue number in PDB)
T790 G793
Binding residue
(residue number reindexed from 1)
T583 G586
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0034511 U3 snoRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0030686 90S preribosome
GO:0030688 preribosome, small subunit precursor
GO:0030692 Noc4p-Nop14p complex
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5wlc, PDBe:5wlc, PDBj:5wlc
PDBsum5wlc
PubMed28945246
UniProtQ99207|NOP14_YEAST Nucleolar complex protein 14 (Gene Name=NOP14)

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