Structure of PDB 6tc3 Chain SPE1 Binding Site BS02

Receptor Information
>6tc3 Chain SPE1 (length=34) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MENNSRTMPHIRRTTHIMKFAHRNSFDFHFFNAR
Ligand information
Ligand IDORN
InChIInChI=1S/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/t4-/m0/s1
InChIKeyAHLPHDHHMVZTML-BYPYZUCNSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6C(C[C@@H](C(=O)O)N)CN
CACTVS 3.370NCCC[CH](N)C(O)=O
CACTVS 3.370NCCC[C@H](N)C(O)=O
ACDLabs 12.01O=C(O)C(N)CCCN
OpenEye OEToolkits 1.7.6C(CC(C(=O)O)N)CN
FormulaC5 H12 N2 O2
NameL-ornithine
ChEMBLCHEMBL446143
DrugBankDB00129
ZINCZINC000001532530
PDB chain6tc3 Chain 23S1 Residue 3001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6tc3 Ornithine capture by a translating ribosome controls bacterial polyamine synthesis.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		H10 R12
Binding residue
(residue number reindexed from 1)		H10 R12
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006417 regulation of translation
GO:0006448 regulation of translational elongation
GO:0031556 transcriptional attenuation by ribosome

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Molecular Function
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Biological Process
External links
PDB RCSB:6tc3, PDBe:6tc3, PDBj:6tc3
PDBsum6tc3
PubMed32094585
UniProtP0DTV7|SPEFL_ECOLI Leader peptide SpeFL (Gene Name=speFL)

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