Structure of PDB 8rxx Chain SK Binding Site BS02

Receptor Information
>8rxx Chain SK (length=198) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GIVRSRLHKRKITGGKTKIHRKRMKAELGRLPANTRLGARRVSPVRARGG
NFKIRALRLDTGNFAWASEAIAHRVRLLDVVYNATSNELVRTKTLVKNCI
VAVDAAPFKRWYAKHYGIDLDADKDKYDVNKASPKLQREWTRRRRNHRVE
KAIADQLREGRVLARITSRPGQSGRADGILLEGAELQFYLKRLEKKKK
Ligand information
>8rxx Chain L5 (length=122) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuacgucccucuccaaacgagagaacaugcaugggcuggcaugagcggca
ugcuucuccgguggggcucgacgucccgaggcgcugaaccuugaggccug
aaaauucaugcucagggacacc
....<<<<<<<<<.......>>>>....<<<<<<<<.<<.....<<<...
..............<<..<<.>>..>>....>>>....>>.....>>>..
......>>>>>...>>>>>...
Receptor-Ligand Complex Structure
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PDB8rxx Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
Resolution2.97 Å
Binding residue
(original residue number in PDB)		R77 L79
Binding residue
(residue number reindexed from 1)		R76 L78
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8rxx, PDBe:8rxx, PDBj:8rxx
PDBsum8rxx
PubMed38722744
UniProtP25204|RS8_LEIMA Small ribosomal subunit protein eS8 (Gene Name=RPS8A)

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