Structure of PDB 8fky Chain SI Binding Site BS02
Receptor Information
>8fky Chain SI (length=229) Species:
9606
(Homo sapiens) [
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KIPLVPENLLKKRKAYQALKATQAKQALLARFKRLESFLHDSWRQKRDKV
RLRRLEVKPHALELPDKHSLAFVVRIERIDGVSLLVQRTIARLRLKKIFS
GVFVKVTPQNLKMLRIVEPYVTWGFPNLKSVRELILKRGQAKVKNKTIPL
TDNTVIEEHLGKFGVICLEDLIHEIAFPGKHFQEISWFLCPFHLSVARHA
TKNRVGFLKEMGTPGYRGERINQLIRQLN
Ligand information
>8fky Chain L2 (length=69) [
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gccgaucaaucgcccccggggugcgcggcugggggcucgcagggccccuc
cgucccccuaagcgcagac
..........<<<<<<..>>>.>>>.....<<<<<..<<.<<<<.>>>>.
>>.>>>>>...........
Receptor-Ligand Complex Structure
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PDB
8fky
Principles of human pre-60 S biogenesis.
Resolution
2.67 Å
Binding residue
(original residue number in PDB)
L65 H66 W69 R70 K72 R73 V76 R79 R80 K84 P85 R104 D106 R230
Binding residue
(residue number reindexed from 1)
L39 H40 W43 R44 K46 R47 V50 R53 R54 K58 P59 R78 D80 R204
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
GO:0003735
structural constituent of ribosome
GO:0005515
protein binding
Biological Process
GO:0000463
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0001825
blastocyst formation
Cellular Component
GO:0005730
nucleolus
GO:0005739
mitochondrion
GO:0005840
ribosome
GO:0022625
cytosolic large ribosomal subunit
GO:1990904
ribonucleoprotein complex
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Molecular Function
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Cellular Component
External links
PDB
RCSB:8fky
,
PDBe:8fky
,
PDBj:8fky
PDBsum
8fky
PubMed
37410842
UniProt
Q6DKI1
|RL7L_HUMAN Ribosomal protein uL30-like (Gene Name=RPL7L1)
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