Structure of PDB 8fku Chain SI Binding Site BS02

Receptor Information
>8fku Chain SI (length=228) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IPLVPENLLKKRKAYQALKATQAKQALLARFKRLESFLHDSWRQKRDKVR
LRRLEVKPHALELPDKHSLAFVVRIERIDGVSLLVQRTIARLRLKKIFSG
VFVKVTPQNLKMLRIVEPYVTWGFPNLKSVRELILKRGQAKVKNKTIPLT
DNTVIEEHLGKFGVICLEDLIHEIAFPGKHFQEISWFLCPFHLSVARHAT
KNRVGFLKEMGTPGYRGERINQLIRQLN
Ligand information
>8fku Chain L2 (length=69) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gccgaucaaucgcccccggggugcgcggcugggggcucgcagggccccuc
cgucccccuaagcgcagac
..........<<<<<<..>>>.>>>.....<<<<<..<<.<<<<.>>>>.
>>.>>>>>...........
Receptor-Ligand Complex Structure
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PDB8fku Principles of human pre-60 S biogenesis.
Resolution2.82 Å
Binding residue
(original residue number in PDB)		L65 H66 W69 R70 K72 R73 V76 R79 R80 P85 H86 R104 D106 R230
Binding residue
(residue number reindexed from 1)		L38 H39 W42 R43 K45 R46 V49 R52 R53 P58 H59 R77 D79 R203
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0001825 blastocyst formation
Cellular Component
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fku, PDBe:8fku, PDBj:8fku
PDBsum8fku
PubMed37410842
UniProtQ6DKI1|RL7L_HUMAN Ribosomal protein uL30-like (Gene Name=RPL7L1)

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