Structure of PDB 7mq8 Chain SB Binding Site BS02

Receptor Information
>7mq8 Chain SB (length=440) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLVLFETSVGYAIFKVLNEKKLQEVDSLWKEFETPEKANKIVKLKHFEKF
QDTAEALAAFTALMEGKINKQLKKVLKKIVKEAHEPLAVADAKLGGVIKE
KLNLSCIHSPVVNELMRGIRSQMDGLIPGVEPREMAAMCLGLAHSLSRYR
LKFSADKVDTMIVQAISLLDDLDKELNNYIMRCREWYGWHFPELGKIISD
NLTYCKCLQKVGDRKNYASAKLSELLPEEVEAEVKAAAEISMGTEVSEED
ICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIA
HAGSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQT
SPKHKGKISRMLAAKTVLAIRYDAFGEDSSSAMGVENRAKLEARLRTLED
RGIRKISGTGKALAKTEKYEHKSEVKTYDPSGDSTLPTCS
Ligand information
>7mq8 Chain L2 (length=215) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gacuauacuuucagggaucauuucuauaguguguuacuagagaaguuucu
cugaacguguagagcaccgaaaaccacgaggaagagagguagcguuuucu
ccugagcgugaagccggcuuucuggcguugcuuggcugcaacugccguca
gccauugaugaucguucuucucuccguauuggggagugagagggagagaa
cgcggucugaguggu
..................................................
.......................<<<<.....<<.......<<<<<<<<<
<<<....<.......<<<<....<<<<<<<<......>>>>>.>>>...>
>>>.........>..<<<<<<<<<<.....>>>>>>.>>>>>>>>>>>>>
>>>...>>..>>>>.
Receptor-Ligand Complex Structure
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PDB7mq8 Nucleolar maturation of the human small subunit processome.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		D170 R297 Q317 A321 K323 A324 F326 R327 R333 D334 T335 P336 K337 Y338 Y342 H343 G356 K357 R360 A364 K365 R404 T409 K411
Binding residue
(residue number reindexed from 1)		D170 R297 Q317 A321 K323 A324 F326 R327 R333 D334 T335 P336 K337 Y338 Y342 H343 G356 K357 R360 A364 K365 R404 T409 K411
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001094 TFIID-class transcription factor complex binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0030515 snoRNA binding
GO:0051117 ATPase binding
Biological Process
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
GO:0048254 snoRNA localization
Cellular Component
GO:0001650 fibrillar center
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005732 sno(s)RNA-containing ribonucleoprotein complex
GO:0005829 cytosol
GO:0015030 Cajal body
GO:0016020 membrane
GO:0031428 box C/D methylation guide snoRNP complex
GO:0032040 small-subunit processome
GO:0070761 pre-snoRNP complex
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7mq8, PDBe:7mq8, PDBj:7mq8
PDBsum7mq8
PubMed34516797
UniProtQ9Y2X3|NOP58_HUMAN Nucleolar protein 58 (Gene Name=NOP58)

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