Structure of PDB 7mq9 Chain SA Binding Site BS02

Receptor Information
>7mq9 Chain SA (length=396) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VLLHVLFEHAVGYALLALKEVEEISLLQPQVEESVLNLGKFHSIVRLVAF
CPFASSQVALENANAVSEGVVHEDLRLLLETHLPSKVLLGVGDPKIGAAI
QEELGYNCQTGGVIAEILRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSR
AKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGYHFPELVKII
NDNATYCRLAQFIGNRRELNEDKLEKLEELTMDGAKAKAILDASRSSMGM
DISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAV
GARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKHSTFIGRAAAKNKG
RISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGE
Ligand information
>7mq9 Chain L2 (length=215) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gacuauacuuucagggaucauuucuauaguguguuacuagagaaguuucu
cugaacguguagagcaccgaaaaccacgaggaagagagguagcguuuucu
ccugagcgugaagccggcuuucuggcguugcuuggcugcaacugccguca
gccauugaugaucguucuucucuccguauuggggagugagagggagagaa
cgcggucugaguggu
..................................................
.......................<<<<.....<<.......<<<<<<<<<
<<<....<.......<<<<....<<<.<<<<......>>>>..>>>...>
>>>.........>..<<<<<<<<<<.....>>>>>>.>>>>>>>>>>>>>
>>>...>>..>>>>.
Receptor-Ligand Complex Structure
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PDB7mq9 Nucleolar maturation of the human small subunit processome.
Resolution3.87 Å
Binding residue
(original residue number in PDB)
K180 S324 I328 R337 K365 R370
Binding residue
(residue number reindexed from 1)
K176 S320 I324 R333 K349 R354
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0030515 snoRNA binding
GO:0045296 cadherin binding
GO:1990226 histone methyltransferase binding
Biological Process
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0001650 fibrillar center
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005732 sno(s)RNA-containing ribonucleoprotein complex
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0031428 box C/D methylation guide snoRNP complex
GO:0032040 small-subunit processome
GO:0070761 pre-snoRNP complex
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7mq9, PDBe:7mq9, PDBj:7mq9
PDBsum7mq9
PubMed34516797
UniProtO00567|NOP56_HUMAN Nucleolar protein 56 (Gene Name=NOP56)

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