Structure of PDB 7mq8 Chain SA Binding Site BS02

Receptor Information
>7mq8 Chain SA (length=396) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VLLHVLFEHAVGYALLALKEVEEISLLQPQVEESVLNLGKFHSIVRLVAF
CPFASSQVALENANAVSEGVVHEDLRLLLETHLPSKVLLGVGDPKIGAAI
QEELGYNCQTGGVIAEILRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSR
AKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGYHFPELVKII
NDNATYCRLAQFIGNRRELNEDKLEKLEELTMDGAKAKAILDASRSSMGM
DISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAV
GARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKHSTFIGRAAAKNKG
RISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGE
Ligand information
>7mq8 Chain L2 (length=215) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gacuauacuuucagggaucauuucuauaguguguuacuagagaaguuucu
cugaacguguagagcaccgaaaaccacgaggaagagagguagcguuuucu
ccugagcgugaagccggcuuucuggcguugcuuggcugcaacugccguca
gccauugaugaucguucuucucuccguauuggggagugagagggagagaa
cgcggucugaguggu
..................................................
.......................<<<<.....<<.......<<<<<<<<<
<<<....<.......<<<<....<<<<<<<<......>>>>>.>>>...>
>>>.........>..<<<<<<<<<<.....>>>>>>.>>>>>>>>>>>>>
>>>...>>..>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7mq8 Nucleolar maturation of the human small subunit processome.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		K180 S324 I328 R337 R370
Binding residue
(residue number reindexed from 1)		K176 S320 I324 R333 R354
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0030515 snoRNA binding
GO:0045296 cadherin binding
GO:1990226 histone methyltransferase binding
Biological Process
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0001650 fibrillar center
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005732 sno(s)RNA-containing ribonucleoprotein complex
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0031428 box C/D methylation guide snoRNP complex
GO:0032040 small-subunit processome
GO:0070761 pre-snoRNP complex
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7mq8, PDBe:7mq8, PDBj:7mq8
PDBsum7mq8
PubMed34516797
UniProtO00567|NOP56_HUMAN Nucleolar protein 56 (Gene Name=NOP56)

[Back to BioLiP]