Structure of PDB 6x89 Chain S8 Binding Site BS02

Receptor Information

>6x89 Chain S8 (length=181) Species: 157791 (Vigna radiata)

TKLEDEQREQLAKEISKDWSSVFERSINTLFLTEMVRGLMLTLKYFFETK
VTINYPFEKGPLSPRFRGEHALRRYPTGEERCIACKLCEAICPAQAITIE
AEEREDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFATETHE
ELLYDKEKLLENGDRWETEIAENLRSESLYR

Ligand information

• Ligand ID: SF4
• InChI: InChI=1S/4Fe.4S
• InChIKey: LJBDFODJNLIPKO-UHFFFAOYSA-N
• SMILES:
  OpenEye OEToolkits 2.0.7: [S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
  CACTVS 3.385: S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
• Formula: Fe4 S4
• Name: IRON/SULFUR CLUSTER
• PDB chain: 6x89 Chain S8 Residue 302

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6x89 Atomic structure of a mitochondrial complex I intermediate from vascular plants.
• Resolution: 3.9 Å
• Binding residue (original residue number in PDB): C123 I124 A125 C126 C129 C172 P173 A176 I177
• Binding residue (residue number reindexed from 1): C82 I83 A84 C85 C88 C131 P132 A135 I136
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0003954 NADH dehydrogenase activity
• GO:0016651 oxidoreductase activity, acting on NAD(P)H
• GO:0046872 metal ion binding
• GO:0051539 4 iron, 4 sulfur cluster binding

Biological Process

• GO:0006120 mitochondrial electron transport, NADH to ubiquinone
• GO:0032981 mitochondrial respiratory chain complex I assembly

Cellular Component

• GO:0005739 mitochondrion
• GO:0016020 membrane

External links

• PDB: RCSB:6x89, PDBe:6x89, PDBj:6x89
• PDBsum: 6x89
• PubMed: 32840211
• UniProt: A0A1S3VGS8