Structure of PDB 8wib Chain S Binding Site BS02

Receptor Information
>8wib Chain S (length=111) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NTLDFVDQASLRDDIPTFSPGDTVNVHVKVIEGSKERIQVFKGVVIRRQG
GGISETFTVRKESYGVGVERTFPVHSPNIDHIDVLTRGDVRRAKLYYLRE
LRGKKAKIKEK
Ligand information
>8wib Chain a (length=1515) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuggagaguuugauccuggcucaggacgaacgcuggcggcgugcuuaaca
caugcaagucgaacggaaaggcccuuucggggguacucgaguggcgaacg
ggugaguaacacgugggugaucugcccugcacuuugggauaagccuggga
aacugggucuaauaccgaauacacccugcuggucgcauggccugguaggg
gaaagcuuuugcggugugggaugggcccgcggccuaucagcuuguuggug
gggugauggccuaccaaggcgacgacggguagccggccugagagggugac
cggccacacugggacugagauacggcccagacuccuacgggaggcagcag
uggggaauauugcacaaugggcgcaagccugaugcagcgacgccgcguga
gggaugacggccuucggguuguaaaccucuuucagcacagacgaagcgca
agugacgguaugugcagaagaaggaccggccaacuacgugccagcagccg
cgguaauacguaggguccgagcguuguccggaauuacugggcguaaagag
cucguaggugguuugucgcguuguucgugaaaacucacagcuuaacugug
ggcgugcgggcgauacgggcagacuagaguacugcaggggagacuggaau
uccugguguagcgguggaaugcgcagauaucaggaggaacaccgguggcg
aaggcgggucucugggcaguaacugacgcugaggagcgaaagcgugggga
gcgaacaggauuagauacccugguaguccacgccguaaacgguggguacu
agguguggguuuccuuccuugggauccgugccguagcuaacgcauuaagu
accccgccuggggaguacggccgcaaggcuaaaacucaaaggaauugacg
ggggcccgcacaagcggcggagcauguggauuaauucgaugcaacgcgaa
gaaccuuaccuggguuugacaugcacaggacgccggcagagaugucgguu
cccuuguggccugugugcagguggugcauggcugucgucagcucgugucg
ugagauguuggguuaagucccgcaacgagcgcaacccuugucucauguug
ccagcacguuaugguggggacucgugagagacugccggggucaacucgga
ggaagguggggaugacgucaagucaucaugccccuuauguccagggcuuc
acacaugcuacaauggccgguacaaagggcugcgaugccgugagguggag
cgaauccuuucaaagccggucucaguucggaucggggucugcaacucgac
cccgugaagucggagucgcuaguaaucgcagaucagcaacgcugcgguga
auacguucccgggccuuguacacaccgcccgucacgucaugaaagucggu
aacacccgaagccgguggccuaacccuuguggagggagccgucgaaggug
ggaucggcgauugggacgaagucguaacaagguagccguaccggaaggug
cggcuggaucaccuc
.....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<
<.<<<..<<<..<<.<..<<<<<<<....>>>>>.>>>..>>>>>.....
.<<........<<<<<<<..<<...<<<<<<<<<<<<.....<<<<<<..
..>>>>>>......>>>>.....<<<<<<<<<<<<..>>>>>.>>>>>>>
....<<....>>>>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<
<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...
>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>
>>.........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<
<<......<<<<....>>>>.....>>>>...<.<<<<<......<<...
.>>.......>>>>>....>..<<<<<(((...<<<<<.....<<.)))>
>.......>>>>>>>>>>..>>>>>>>>>..........<<<((.....<
<<<...<<<.<<<<<<<.<<<<<<<<<<.....<<<<<<<.....>>>>>
>>...>>>>>>>..>>>>>>>>>>...<<<<<<<<...<<<<<<<....<
<<<<<<<<..<<<......>>>.....>>>>>>>>>...........<<.
...>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<...
<<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<<<<.
.<<<<<<<<<<<<.......>>>>>>>>>>>>...<<..))>>.....>>
>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<
.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>..
........<<<<<<<......<<<<<<<...<<<<<<<....>>>>>>>.
<<.....>>.>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<.
...>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<....
<<..<<<......>>>>>.....>>>>>>.....<<<<<.....>>>>>.
.......>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>
.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>..>
>....>>>......>>>>>>>......<....<<<<<<<........>>>
>>>>....>.....>>>>>>....<<<<<<<..........>>>>>>>..
....>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<
..<<<<....<.<<<<..<<<..<<.....>>.>>>.>>>>.>...>>>>
..>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>
>>>>>..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8wib Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
R38 Q40 K105
Binding residue
(residue number reindexed from 1)
R37 Q39 K104
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8wib, PDBe:8wib, PDBj:8wib
PDBsum8wib
PubMed38245551
UniProtA0QV42|RL19_MYCS2 Large ribosomal subunit protein bL19 (Gene Name=rplS)

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