Structure of PDB 8atf Chain S Binding Site BS02

Receptor Information
>8atf Chain S (length=107) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAE
ILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNI
QAVLLPK
Ligand information
>8atf Chain L (length=143) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggatgtatatatctgacacgtgcctggagactagggagtaatccccttgg
cggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgctagag
ctgtctacgaccaattgagcggcctcggcaccgggattctcca
Receptor-Ligand Complex Structure
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PDB8atf Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Resolution3.45 Å
Binding residue
(original residue number in PDB)
A14 K15 R17 R20 R32 R77
Binding residue
(residue number reindexed from 1)
A3 K4 R6 R9 R21 R66
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0019899 enzyme binding
GO:0030527 structural constituent of chromatin
GO:0031492 nucleosomal DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0008150 biological_process
GO:0031507 heterochromatin formation
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0070062 extracellular exosome

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Biological Process

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Cellular Component
External links
PDB RCSB:8atf, PDBe:8atf, PDBj:8atf
PDBsum8atf
PubMed36490333
UniProtP0C0S8|H2A1_HUMAN Histone H2A type 1 (Gene Name=H2AC11)

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