Structure of PDB 7as8 Chain S Binding Site BS02

Receptor Information

>7as8 Chain S (length=120) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168)

MITKTSKNAARLKRHARVRAKLSGTAERPRLNVFRSNKHIYAQIIDDVNG
VTLASASTLDKDLNVESTGDTSAATKVGELVAKRAAEKGISDVVFDRGGY
LYHGRVKALADAAREAGLKF

Ligand information

>7as8 Chain B (length=112)

ugguggcgauagcgaagaggucacacccguucccauaccgaacacggaag
uuaagcucuucagcgccgaugguagucggggguuucccccugugagagua
ggacgccgccaa

<<<<<<<....<<<<<<<<.....<<<<<...............>>>..>
>....>>>>>>.>>.<<.....<.<<.<<<<<...>>>>>.>>...>...
>>..>>>>>>>.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7as8 Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP.
• Resolution: 2.9 Å
• Binding residue (original residue number in PDB): K7 R11 H15 R19 R30 N32 F34 R35 S36 N37 K38 H39 Y41 T52 L59 Y100 L101 H103 G104 R105
• Binding residue (residue number reindexed from 1): K7 R11 H15 R19 R30 N32 F34 R35 S36 N37 K38 H39 Y41 T52 L59 Y100 L101 H103 G104 R105

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0008097 5S rRNA binding
• GO:0019843 rRNA binding

Biological Process

• GO:0006364 rRNA processing
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7as8, PDBe:7as8, PDBj:7as8
• PDBsum: 7as8
• PubMed: 33259810
• UniProt: P46899|RL18_BACSU Large ribosomal subunit protein uL18 (Gene Name=rplR)