Structure of PDB 4wfa Chain S Binding Site BS02

Receptor Information

>4wfa Chain S (length=167) Species: 367830 (Staphylococcus aureus subsp. aureus USA300) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVI
REVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTV
EVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNIND
SLTVADVKVTGDFKIEN

Ligand information

>4wfa Chain Y (length=114) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ucuggugacuauagcaaggaggucacaccuguucccaugccgaacacaga
aguuaaggucuuuagcgacgaugguagccaacuuacguuccgcuagagua
gaacguugccaggc

.<<.<..<.....<<<<<<<......<<<<<...............>>>.
.>>.....>>>>>.>><.........<.<............>.>......
...>..>..>.>>.

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4wfa Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Resolution	3.392 Å
Binding residue (original residue number in PDB)	D17 R22 V30 Y32 N38 Q78 H88 D90
Binding residue (residue number reindexed from 1)	D15 R20 V28 Y30 N36 Q76 H86 D88

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0008097	5S rRNA binding
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Cellular Component

External links

PDB	RCSB:4wfa, PDBe:4wfa, PDBj:4wfa
PDBsum	4wfa
PubMed	26464510
UniProt	Q2FJE0\|RL25_STAA3 Large ribosomal subunit protein bL25 (Gene Name=rplY)

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