Structure of PDB 7r81 Chain R1 Binding Site BS02

Receptor Information

>7r81 Chain R1 (length=168) Species: 5141 (Neurospora crassa)

VRYAATEIAPAKSARSRGSYLRVSFKNTRETAQAINGWKLQRAQKFLENV
LEKKEAVPMRRYAGGTGRAAQGKQFGVSRARWPAKSAEFLLGLLKNAEAN
ADAKGLDTGNLVVKHIQVNQAPKQRRRTYRAHGRINPYMSNPCHIELILT
ELSSRQRGARVRRAITAA

Ligand information

>7r81 Chain C1 (length=158)

aaacuuucaacaacggaucucuugguucuggcaucgaugaagaacgcagc
gaaaugcgauagguaaugugaauugcagaauucagugaaucaucgaaucu
uugaacgcacauugcgcucgccaguauucuggcgagcaugccuguucgag
cgucauuu

.........................................<<<<<<<<<
....>>>>.....<.<<<......>>..............>>>..>...>
>>....<<.....>><<<<<<<<<....>>>>>>>>>.............
........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7r81 Structure of the translating Neurospora ribosome arrested by cycloheximide
• Resolution: 2.7 Å
• Binding residue (original residue number in PDB): A5 R61 R62 N120 Q121 P123
• Binding residue (residue number reindexed from 1): A4 R60 R61 N119 Q120 P122

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0015934 large ribosomal subunit
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7r81, PDBe:7r81, PDBj:7r81
• PDBsum: 7r81
• PubMed: 34815343
• UniProt: Q9HE25|RL17_NEUCR Large ribosomal subunit protein uL22 (Gene Name=rpl-17)