Structure of PDB 8bos Chain R Binding Site BS02

Receptor Information
>8bos Chain R (length=166) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGET
CLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQI
KRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQ
GVEDAFYTLVREIRQH
Ligand information
Ligand IDMGF
InChIInChI=1S/3FH.Mg/h3*1H;/q;;;+2/p-3
InChIKeyGJOMWUHGUQLOAC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Mg-](F)F
FormulaF3 Mg
NameTRIFLUOROMAGNESATE
ChEMBL
DrugBank
ZINC
PDB chain8bos Chain R Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8bos A small G protein with MgF3 TSA complex
Resolution2.1 Å
Binding residue
(original residue number in PDB)		G12 K16 T35 A59 G60 Q61
Binding residue
(residue number reindexed from 1)		G12 K16 T35 A59 G60 Q61
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8bos, PDBe:8bos, PDBj:8bos
PDBsum8bos
PubMed
UniProtP01112|RASH_HUMAN GTPase HRas (Gene Name=HRAS)

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