Structure of PDB 7oif Chain R Binding Site BS02

Receptor Information

>7oif Chain R (length=110) Species: 562 (Escherichia coli)

METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKV
LESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRT
SHITVVVSDR

Ligand information

>7oif Chain B (length=27) Species: 562 (Escherichia coli)

MSGKMTGIVKWFNADKGFGFITPDDGS

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7oif A switch from alpha-helical to beta-strand conformation during co-translational protein folding.
• Resolution: 3.0 Å
• Binding residue (original residue number in PDB): I85 G91 R95
• Binding residue (residue number reindexed from 1): I85 G91 R95

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0005515 protein binding
• GO:0019843 rRNA binding
• GO:0070180 large ribosomal subunit rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation
• GO:0042255 ribosome assembly
• GO:0042256 cytosolic ribosome assembly
• GO:0046677 response to antibiotic
• GO:1902626 assembly of large subunit precursor of preribosome

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0015934 large ribosomal subunit
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7oif, PDBe:7oif, PDBj:7oif
• PDBsum: 7oif
• PubMed: 34994471
• UniProt: P61175|RL22_ECOLI Large ribosomal subunit protein uL22 (Gene Name=rplV)