Structure of PDB 7aqd Chain R Binding Site BS02

Receptor Information
>7aqd Chain R (length=433) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFDGMFTYGMTHELNEKIMGGRITKIHQPYKHDVIFHIRAKGKNQKLLLS
AHPSYSRVHITAQAYENPSEPPMFCMLLRKHIEGGFIEKIEQAGLDRIMI
FHIKSRNEIGDETVRKLYVEIMGRHSNIILTDAAENVIIDGLKHLSPSMN
SYRTVLPGQDYKLPPAQDKISPLEASEDDILRHLSFQEGRLDKQIVDHFS
GVSPLFAKEAVHRAGLANKVTLPKALLALFAEVKEHRFIPNITTVNGKEY
FYLLELTHLKGEARRFDSLSELLDRFYFGKAERDRVKQQAQDLERFVVNE
RKKNANKIKKLEKTLEYSENAKEFQLYGELLTANLYMLKKGDKQAEVINY
YDEESPTITIPLNPNKTPSENAQAYFTKYQKAKNSVAVVEEQIRLAQEEI
EYFDQLIQQLSSASPRDISEIREELVEGKYLRP
Ligand information
>7aqd Chain T (length=76) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggggccuuagcucagcugggagagcgccugcuuugcacgcaggaggucag
cgguucgaucccgcuaggcuccacca
<<<<<<<..<<<<........>>>>.<<<<<.......>>>>>.....<<
<<<.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
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PDB7aqd Mimicry of Canonical Translation Elongation Underlies Alanine Tail Synthesis in RQC.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		D4 H53 P54 S55 D97 R98 I122 M123 G124 R125 H126 S127 Q168 K194 V197 F200 S201 G202 V203 S204 P205 L206 F207 A208 K249 Y251 Y253 D285 K288 Q289 Q290 Q292 D293 E295 R296
Binding residue
(residue number reindexed from 1)		D3 H52 P53 S54 D96 R97 I121 M122 G123 R124 H125 S126 Q167 K193 V196 F199 S200 G201 V202 S203 P204 L205 F206 A207 K248 Y250 Y252 D284 K287 Q288 Q289 Q291 D292 E294 R295
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0043023 ribosomal large subunit binding
Biological Process
GO:0006412 translation
GO:0072344 rescue of stalled ribosome
Cellular Component
GO:1990112 RQC complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7aqd, PDBe:7aqd, PDBj:7aqd
PDBsum7aqd
PubMed33259811
UniProtO34693|RQCH_BACSU Rqc2 homolog RqcH (Gene Name=rqcH)

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