Structure of PDB 7aqc Chain R Binding Site BS02

Receptor Information
>7aqc Chain R (length=558) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFDGMFTYGMTHELNEKIMGGRITKIHQPYKHDVIFHIRAKGKNQKLLLS
AHPSYSRVHITAQAYENPSEPPMFCMLLRKHIEGGFIEKIEQAGLDRIMI
FHIKSRNEIGDETVRKLYVEIMGRHSNIILTDAAENVIIDGLKHLSPSMN
SYRTVLPGQDYKLPPAQDKISPLEASEDDILRHLSFQEGRLDKQIVDHFS
GVSPLFAKEAVHRAGLANKVTLPKALLALFAEVKEHRFIPNITTVNGKEY
FYLLELTHLKGEARRFDSLSELLDRFYFGKAERDRVKQQAQDLERFVVNE
RKKNANKIKKLEKTLEYSENAKEFQLYGELLTANLYMLKKGDKQAEVINY
YDEESPTITIPLNPNKTPSENAQAYFTKYQKAKNSVAVVEEQIRLAQEEI
EYFDQLIQQLSSASPRDISEIREELVEGKYLRPHNPVLETYESTSGLTIL
VGKNNRQNEYLTTRVAARDDIWLHTKDIPGSHVVIRSSEPDEQTIMEAAT
IAAYFSKAKDSSSVPVDYTKIRHVKKPNGAKPGFVTYDSQHTVFVTPDAD
TVIKLKKS
Ligand information
>7aqc Chain P (length=69) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggggccuuagcucaggggagagcgccugcucgcaggaggucagcgguucg
aucccgcuaggcuccacca
<<<<<<<..<<<<......>>>>.<<<<<..>>>>>.....<<<<<....
...>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7aqc Mimicry of Canonical Translation Elongation Underlies Alanine Tail Synthesis in RQC.
Resolution2.99 Å
Binding residue
(original residue number in PDB)
R23 H28 R40 P69 P72 M77 R80
Binding residue
(residue number reindexed from 1)
R22 H27 R39 P68 P71 M76 R79
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0043023 ribosomal large subunit binding
Biological Process
GO:0006412 translation
GO:0072344 rescue of stalled ribosome
Cellular Component
GO:1990112 RQC complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7aqc, PDBe:7aqc, PDBj:7aqc
PDBsum7aqc
PubMed33259811
UniProtO34693|RQCH_BACSU Rqc2 homolog RqcH (Gene Name=rqcH)

[Back to BioLiP]