Structure of PDB 6gen Chain R Binding Site BS02

Receptor Information

>6gen Chain R (length=411) Species: 559292 (Saccharomyces cerevisiae S288C)

ETPPIVIDNGSYEIKFGPSTNKKPFRALNALAKDKFGTSYLSNHIKNIKD
ISSITFRRPHELGQLTLWELESCIWDYCLFNPSEFDGFDLKEGKGHHLVA
SESCMTLPELSKHADQVIFEEYEFDSLFKSPVAVFVPFTKSYKGEMRTIS
GKDESDYHDFQLVIDSGFNCTWIIPVLKGIPYYKAVKKLDIGGRFLTGLL
KETLSFRHYNMMDETILVNNIKEQCLFVSPVSYFDSFKTKDKHALEYVLP
DFQTSFLGYVRNPRKENVPLPEDAQIITLTDELFTIPETFFHPEISQITK
PGIVEAILESLSMLPEIVRPLMVGNIVCTGGNFNLPNFAQRLAAELQRQL
PTDWTCHVSVPEGDCALFGWEVMSQFAKTDSYRKARVTREEYYEHGPDWC
TKHRFGYQNWI

Ligand information

• Ligand ID: BEF
• InChI: InChI=1S/Be.3FH/h;3*1H/q+2;;;/p-3
• InChIKey: OGIAHMCCNXDTIE-UHFFFAOYSA-K
• SMILES:
  OpenEye OEToolkits 1.5.0: [Be-](F)(F)F
  ACDLabs 10.04
  CACTVS 3.341: F[Be-](F)F
• Formula: Be F3
• Name: BERYLLIUM TRIFLUORIDE ION
• PDB chain: 6gen Chain R Residue 502

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6gen Structure and dynamics of the yeast SWR1-nucleosome complex.
• Resolution: 3.6 Å
• Binding residue (original residue number in PDB): G194 N196
• Binding residue (residue number reindexed from 1): G167 N169
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0031491 nucleosome binding

Biological Process

• GO:0006325 chromatin organization
• GO:0006338 chromatin remodeling
• GO:0006355 regulation of DNA-templated transcription

Cellular Component

• GO:0000785 chromatin
• GO:0000812 Swr1 complex
• GO:0005634 nucleus
• GO:0005737 cytoplasm
• GO:0034399 nuclear periphery
• GO:0043232 intracellular non-membrane-bounded organelle

External links

• PDB: RCSB:6gen, PDBe:6gen, PDBj:6gen
• PDBsum: 6gen
• PubMed: 30309918
• UniProt: Q12509|ARP6_YEAST Actin-like protein ARP6 (Gene Name=ARP6)