Structure of PDB 6ff4 Chain R Binding Site BS02

Receptor Information
>6ff4 Chain R (length=102) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERE
RAAAREKNRRWDDDVVFKNCAKGVDDQKKDKRFVNDTLRSEFHKKFMEKY
IK
Ligand information
>6ff4 Chain 6 (length=95) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gugcucgcuucggcagcacauauacuaaaauuggaacgauacagagaaga
uuagcauggccccugcgcaaggaugacacgcaaauucgugaagcg
<<<<<.<<....>>>>>>>...............................
......<<...<<<.....>>>....>>.................
Receptor-Ligand Complex Structure
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PDB6ff4 Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		R33 D34
Binding residue
(residue number reindexed from 1)		R16 D17
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0045292 mRNA cis splicing, via spliceosome
Cellular Component
GO:0000974 Prp19 complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0005739 mitochondrion
GO:0016607 nuclear speck
GO:0071007 U2-type catalytic step 2 spliceosome
GO:0071013 catalytic step 2 spliceosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ff4, PDBe:6ff4, PDBj:6ff4
PDBsum6ff4
PubMed29361316
UniProtQ9P013|CWC15_HUMAN Spliceosome-associated protein CWC15 homolog (Gene Name=CWC15)

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