Structure of PDB 6cnf Chain R Binding Site BS02

Receptor Information
>6cnf Chain R (length=522) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPVCKNCHGTEFERDLSNANNDLVCKACGVVSEDNPIVSEVALESREATL
NNARRKLRAVSYALHIPEYITDAAFQWYKLALANNFVQGRRSQNVIASCL
YVACRKEKTHHMLIDFSSRLQVSVYSIGATFLKMVKKLHITELPLADPSL
FIQHFAEKLDLADKKIKVVKDAVKLAQRMSKDWMFEGRRPAGIAGACILL
ACRMNNLRRTHTEIVAVSHVAEETLQQRLNEFKNTKAAKLSVQKFRENDV
EDGEARPPSFVKNRKKESGIVPTLQNIVATVTLGCRLDLKTVALHARNAE
YNPKRFAAVIMRIREPKTTALIFASGKMVVTGAKSEDDSKLASRKYARII
QKIGFAAKFTDFKIQNIVGSCDVKFPIRLEGLAFSHGTFSSYEPELFPGL
IYRMVKPKIVLLIFVSGKIVLTGAKQREEIYQAFEAIYPVLSEFRKMSGS
PRNLHLLPTTDTYLSKVSDDPDNLEDVDDEELNAHLLNEEASKLKERIWI
GLNADFLLEQESKRLKQEADIA
Ligand information
>6cnf Chain Y (length=57) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acgccttaaccaacttggccatggagtacagaaaaagtattactaatata
tgttgaa
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6cnf Structural visualization of RNA polymerase III transcription machineries.
Resolution4.5 Å
Binding residue
(original residue number in PDB)		L73 G119 R120 R218 R219 V250 A251 T254 Q394 N395 R424 F425 R431 E514 F533 K537
Binding residue
(residue number reindexed from 1)		L43 G89 R90 R188 R189 V220 A221 T224 Q275 N276 R305 F306 R312 E395 F414 K418
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0017025 TBP-class protein binding
Biological Process
GO:0006352 DNA-templated transcription initiation

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Molecular Function
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Biological Process
External links
PDB RCSB:6cnf, PDBe:6cnf, PDBj:6cnf
PDBsum6cnf
PubMed30083386
UniProtP13393|TBP_YEAST TATA-box-binding protein (Gene Name=SPT15);
P29056|TF3B_YEAST Transcription factor IIIB 70 kDa subunit (Gene Name=BRF1)

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