Structure of PDB 6cnc Chain R Binding Site BS02

Receptor Information
>6cnc Chain R (length=522) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPVCKNCHGTEFERDLSNANNDLVCKACGVVSEDNPIVSEVALESREATL
NNARRKLRAVSYALHIPEYITDAAFQWYKLALANNFVQGRRSQNVIASCL
YVACRKEKTHHMLIDFSSRLQVSVYSIGATFLKMVKKLHITELPLADPSL
FIQHFAEKLDLADKKIKVVKDAVKLAQRMSKDWMFEGRRPAGIAGACILL
ACRMNNLRRTHTEIVAVSHVAEETLQQRLNEFKNTKAAKLSVQKFRENDV
EDGEARPPSFVKNRKKESGIVPTLQNIVATVTLGCRLDLKTVALHARNAE
YNPKRFAAVIMRIREPKTTALIFASGKMVVTGAKSEDDSKLASRKYARII
QKIGFAAKFTDFKIQNIVGSCDVKFPIRLEGLAFSHGTFSSYEPELFPGL
IYRMVKPKIVLLIFVSGKIVLTGAKQREEIYQAFEAIYPVLSEFRKMSGS
PRNLHLLPTTDTYLSKVSDDPDNLEDVDDEELNAHLLNEEASKLKERIWI
GLNADFLLEQESKRLKQEADIA
Ligand information
>6cnc Chain Y (length=61) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccatggagtcattttatcttgtgtcacttacagaaaaagtattactaata
tatgttgaaaa
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6cnc Structural visualization of RNA polymerase III transcription machineries.
Resolution4.1 Å
Binding residue
(original residue number in PDB)		L73 R120 R218 R219 A251 E253 T254 Q394 R424 R431 T438 V487 S489 P517 F533 S535 K537 V539
Binding residue
(residue number reindexed from 1)		L43 R90 R188 R189 A221 E223 T224 Q275 R305 R312 T319 V368 S370 P398 F414 S416 K418 V420
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0017025 TBP-class protein binding
Biological Process
GO:0006352 DNA-templated transcription initiation

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Molecular Function
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Biological Process
External links
PDB RCSB:6cnc, PDBe:6cnc, PDBj:6cnc
PDBsum6cnc
PubMed30083386
UniProtP13393|TBP_YEAST TATA-box-binding protein (Gene Name=SPT15);
P29056|TF3B_YEAST Transcription factor IIIB 70 kDa subunit (Gene Name=BRF1)

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