Structure of PDB 5t5h Chain R Binding Site BS02

Receptor Information
>5t5h Chain R (length=152) Species: 5693 (Trypanosoma cruzi) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HYSRKPQVSSKSAKAKVSDLRCHFKNTFETANVINGMPLRKAQQLYRQVL
AKTRCIPFKRYNGKIGRTAQAKEWGQTKGRWPRKSVVAMLSLLKNAEANA
IEKGLDPNKMVIKHVQVDQAARMRRRTYRAHGRITPYMCSPCHVQLFMTQ
PQ
Ligand information
>5t5h Chain B (length=941) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acugcagaccguacucaucaccgcaucagguccccaagcauacaaugcuc
ugguacauagagaaagguacacucagggaagucggcaaaauagaugcgua
aguucgcaagaagcauuggcucugagggcaacaacucagaacugcuuacg
gcggggaauccaacuguauaauuaaaacauagguuugugaugcauccaag
ugguguaugucgcaaacugauuucugcccagugcucugugaagagguuca
ccggcgcggguaaacggcaagguagccaaaugccucgucuuccaauuaga
gacgcgcaugaauggauuaaugagauucccucugucccgaguuacuaucu
agcgaaacgacagucaagggaacggacuugaagggcuaagcggggaaaga
agacccuguugaguuugacuccagucuggcucugugaggcgagcuucacu
uaucgaaugaagagaccaauggguuucgcguagucugcgggcuaugcacc
gucucugaaccaacggagucuuguuucgagacaucugccagauggggagu
uuggcuggggcggcauaucuguuacacgacaacgcagguguccuaaggcg
agcucagugggaucucacguagaacacaagcguaaaagcuugcuugauua
acgauuuccaguacgaaucgagacugcgaaagcaaggccagcgauccuuu
gcguaugaacaaaucauaccagaggugucagaauaauuaccacagggaua
acuggcuuauccuucgaugucggcucuuccuaaccuagcggcuaaggguu
ggauuguucacccacugacagggaacgugagcuggguuuagaccgucgug
agacagguugguuuuacccuacuuagcuggaaauugcgagaaaaaaaaaa
uuuuuuaaaauuuuuuuuuuuuuuacuugguacgaaaaaaa
....................<<......>>......<<<<.....>>>>.
.......<<<<....<<<<.<<<<.<<...............<<<<<...
............>>>>><<.<<<<<<........>>>>>>.>>.......
...<<<<<<<<<..<<<.........>>>..<<<<<<<....<<<<....
.>>>>......>>>>>>>...<<...<<..<<<<<<.<<<<<....>>>>
>......>>>>..>>>>.......<...........<<<<<.......>>
>>>.....>.....>>....>>.>>>>>>>.....>>.>>>>>>>>.>>>
>............<<<<<........>>>>>..<<<<<<<..<<<.<<..
....<<<<.<.<<<<..<<<<<.<<<<<<<...<<<<<<<..>>>>>>>.
..<<<<<.....<<<<....<<.....<<<<<<<......>>>>>>>.>>
.................>>>>...>>>>>.......>>>>>>>..>>>>>
...<<<.....>>>..<<<<<<...........>>>>>>..<<...<<<<
<<<...<<<<<..>>>>>.....<<......>>....>>>>>>>...<<.
..<<<<<.......>>>>>..>>.<<<....>>>.>>........<<<<<
<.<<<<<.......>>>>>>>>>>>.........>>>>...>>>>>....
...<<....>.>.......<<<<<.<<<<<<..<<<<<<.>>>>..>>.<
<<.........>>>.....>>>>>..>...>>>.>>....<<<<<<<...
.>>>.>>>>....>>..>>>.>>>>>>>..................<<<.
.>>>..<<...>>.<<<<<<...<.......>...>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5t5h Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit.
Resolution2.54 Å
Binding residue
(original residue number in PDB)		H25 K54 G65 K66 I67 G68 R69 T79 K80 R82 W83 P84 R85 K86 Y130 R131 G134 R135 I136 T137 P138 Y139 M140 C141
Binding residue
(residue number reindexed from 1)		H23 K52 G63 K64 I65 G66 R67 T77 K78 R80 W81 P82 R83 K84 Y128 R129 G132 R133 I134 T135 P136 Y137 M138 C139
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5t5h, PDBe:5t5h, PDBj:5t5h
PDBsum5t5h
PubMed27791004
UniProtQ4DC23

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