Structure of PDB 7vxp Chain Q Binding Site BS02

Receptor Information
>7vxp Chain Q (length=386) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNLTLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGTEKLIEYK
TYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEI
TRLLNHIMAVTTHALDIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYI
RPGGVHQDLPLGLLDDIYEFSKNFSFRIDELEEMLTNNRIWRNRTVDIGV
VTAEDALNYGFSGVMLRGSGIQWDLRKTQPYDVYDQVEFDVPIGSRGDCY
DRYLCRVEEMRQSLRIISQCLNKMPPGEIKVDDAKVSPPKRAEMKTSMES
LIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAP
GFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7vxp Chain C Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7vxp The coupling mechanism of mammalian mitochondrial complex I.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		X118 R138 H223
Binding residue
(residue number reindexed from 1)		X41 R61 H146
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0048038 quinone binding
GO:0051287 NAD binding

View graph for
Molecular Function
External links
PDB RCSB:7vxp, PDBe:7vxp, PDBj:7vxp
PDBsum7vxp
PubMed35145322
UniProtF1S1A8

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